VAX 11/750 COMPUTER CENTER FOR ANALYSIS OF PRIMARY DNA

这项拨款是用于购买一套以VAX 11/750为基础的电脑系统 主要用于分析原始DNA、RNA和蛋白质序列数据 使用现在可用的强大软件系统。 该系统将包括 VAX 11/750小型机、磁带机、硬盘、八彩虹 100台微型计算机（用作智能终端），VT 241图形终端， 和打印机。 在选择购买的计算机系统时， 并设计了兼容的系统。 最 在VAX计算机上运行的功能强大的程序 在VMS操作系统（Devereux的U.威斯康星州的项目， 例如，Staden的程序和NIH的Dayhoff系统）。 这些 程序要么在公共领域，要么在合理的时间内可用。 费 VAX计算机将被安置在生物工程设施， 康涅狄格大学健康中心已经运营了几个 PDP-11电脑 将通过电话与研究者联系。 计算机的操作将由一个由三个人组成的小组监督， investigators. 该机器将提供给健康中心 科学工作人员作为一个整体或从大学以外的其他人 如果机器没有被占用与主要工作有关的工作， 这里描述的项目。 本申请中描述的系统将提供给卫生部 中心分子生物学社区的国家的最先进的小学和 二级序列分析计算机系统。 我们一直在一个独特的 没有这样的制度是不好的。 购买该系统将 大大加强了我们的研究工作。

This grant is for the purchase of a VAX11/750 based computer system primarily for use in analyzing primary DNA, RNA and protein sequence data using the powerful software systems now available. The system will include the VAX 11/750 minicomputer, magnetic tape drive, hard disc, eight Rainbow 100 microcomputers (to act as smart terminals), VT241 graphics terminal, and printers. In choosing the computer system for purchase we have focused on the software available and designed the system to be compatible. Most of the powerful programs available operate on a VAX computer operating under the VMS operating system (Devereux's U. of Wisconsin programs, Staden's programs, and the Dayhoff system of the NIH, for example). These programs are either in the public domain or are available for a reasonable fee. The VAX computer will be housed in the Bioengineering facility of the University of Connecticut Health Center which already operates several PDP-11 computers. Connection to the investigators will be via telephone. The operation of the computer will be overseen by a group of three of the investigators. The machine will be available to the Health Center scientific staff as a whole or to others from outside the University provided that the machine is not occupied with work pertaining to the major projects described here. The system described in this application will make available to the Health Center molecular biology community the state-of-the-art in primary and secondary sequence analysis computer systems. We have been at a distinct disadvantage in not having such a system. Purchase of this system will greatly enhance our research effort.