VAX-11/780 COMPUTER SYSTEM

加州大学精神发育迟滞研究中心 加利福尼亚州、洛杉矶开展精神发育迟滞及相关研究 人的发展的各个方面，使用各种学科方法。 这些研究的范围从对智障人士的人类学研究到 遗传性代谢性疾病的分子方面。我们的研究是 以强烈的互动努力为特征的，在这种努力中，来自 不同的学科解决共同感兴趣的问题。除了……之外 我们的研究任务，MRRC作为一个教学单位非常活跃，特别是 在我们的研究生和博士后研究培训活动中 实习生。本申请书是为收购 研究持续增长所需的计算机系统 MRRC的计划。 目前，我们的研究由四台PDP-11计算机、各种 微处理器和远程作业进入加州大学洛杉矶分校的校园计算设施。 这些安排是不充分的。他们不允许使用最新的 我们可以使用的计算方法。遗传学与神经生理学 项目在技术上处于停滞状态。重要的是我们必须获得 很快显著提高了计算能力。中央设施非常好 成本高昂，任何一个研究项目都负担不起 足够大的计算机。核心支持拨款已经严重不足 在成本迅速增加的时期，受到资金水平的限制。 空间可用，由加州大学洛杉矶分校提供维护。一个 可以使用经验丰富的程序员和统计学家进行开发 并使用新系统。几个最有前途的研究项目 受到计算资源严重限制的阻碍；替代方案 这些方法要么更昂贵，要么技术更复杂。我们需要的是 本提案所要求的一台足够的计算机。

The Mental Retardation Research Center (MRRC) of the University of California, Los Angeles conducts research on mental retardation and related aspects of human development, using a variety of disciplinary approaches. These range from anthropological studies of mentally retarded persons to molecular aspects of inherited metabolic diseases. Our research is characterized by strong interactive efforts in which scientists from different disciplines attack problems of common interest. In addition to our research mission, the MRRC is active as a teaching unit, particularly in our research training activity for graduate students and postdoctoral trainees. This application is a request for funding for the acquisition of the computer system required by the continuing growth of the research programs of the MRRC. Currently, our research is supported by four PDP-11 computers, a variety of micro-processors and remote job entry to UCLA campus computing facilities. These arrangements are inadequate. They do not permit use of the latest computational methods available to us. The genetics and neurophysiology projects are at a technological standstill. It is essential that we obtain significantly increased computing power soon. Central facilities are very costly, and no single research project can afford to purchase a sufficiently large computer. The core support grant has been severely restricted by level funding during a period of rapidly increasing costs. Space is availabale and maintenance would be provided by UCLA. An experienced staff of programmers and statisticians are available to develop and use the new system. Several of the most promising research projects are hampered by serious limitations on computing resources; alternative approaches are more expensive or technologically complex. What we need is an adequate computer, as requested by this proposal.