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Combination immunotherapeutic strategies for haematological cancers

Combination immunotherapeutic strategies for haematological cancers
血液癌症的联合免疫治疗策略
批准号:
nhmrc : 1061429
负责人:
Dr Stephen Mattarollo
金额:
$28.12万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31

项目摘要

项目成果

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中文摘要
翻译
淋巴瘤患者最初对治疗反应良好,但后来病情复发。免疫系统可以有效地控制癌症。一种潜在的治疗选择是增强对癌症的自然免疫反应。本研究研究了一种新型疫苗,该疫苗通过传递NKT细胞激活分子来激活某种免疫细胞NKT细胞来对抗淋巴瘤。结果将允许评估基于nkt的疫苗与现有淋巴瘤治疗方法的结合。
英文摘要
Patients with lymphoma cancers initially respond well to treatment, but later relapse with disease. The immune system can be effective at controlling cancer. A potential treatment option is to boost the natural immune response against cancer. This study investigates a novel vaccine that activates a certain immune cell, NKT cells, to fight lymphomas by delivering an NKT cell-activating molecule. Outcomes will allow assessment of combining an NKT-based vaccine with established treatments for lymphoma.
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Developing immune-based therapies for blood cancers
  • 批准号:
    nhmrc : GNT1061429
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $40.49万
  • 财政年份:
    2014
  • 负责人:
    Dr Stephen Mattarollo
  • 依托单位:
Therapeutic vaccine against non-Hodgkin's lymphoma targeting the immune adjuvant properties of Natural Killer T cells.
  • 批准号:
    nhmrc : 1044355
  • 项目类别:
    Project Grants
  • 资助金额:
    $30.11万
  • 财政年份:
    2013
  • 负责人:
    Dr Stephen Mattarollo
  • 依托单位:
海外基金