Combinatorial therapeutics in high-risk infant acute lymphoblastic leukaemia

白血病儿童的现代疗法治愈率超过90%。相比之下，诊断时不到一岁的婴儿存活率不到50%。迫切需要更好的治疗方法。通过实验室测试，我们发现了有效的新型抗癌药物，目前还没有用于治疗患有白血病的婴儿。我们将评估新的药物组合，并在模型系统中进行测试，以便它们可以快速进入临床。

Modern therapies for children with leukaemia are curative in more than 90%. In contrast, survival for infants less than one year of age at the time of diagnosis is less than 50%. Better therapies are desperately needed. From laboratory testing we have discovered effective novel cancer drugs, which are not currently used for treatment of babies with leukaemia. We will evaluate novel drug combinations and test them in model systems, such that they can be fast-tracked to the clinic.