Comparative effectiveness of breast tomosynthesis and mammography in real-world population screening: Evidence to underpin and improve breast cancer screening

这项研究通过研究断层合成(3D乳房X光摄影)和标准2D乳房X光检查来解决乳腺癌筛查中的关键证据空白，以确定断层合成在澳大利亚和国际上的有效性，包括对临床进展的筛查中未发现的癌症的影响。将在现实世界的筛查服务中进行大规模研究，包括与BreastScreen合作计划的前瞻性比较研究，以指导筛查政策。

This research addresses key evidence gaps in breast cancer screening by investigating tomosynthesis (3D mammography) versus standard 2D mammography screening to establish the effectiveness of tomosynthesis in Australia and internationally, including impact on cancers not detected at screening that progress clinically. Large-scale studies will be done in real world screening services including a prospective comparative study planned collaboratively with BreastScreen to guide screening policy.