PREPARATION OF ANTI-AIDS DRUGS

该项目用于制备已知的化学品和原料药， 是临床应用所需要的。 选择的化合物 所需的质量或数量不容易获得 从原始供应商或在公开市场上。 该项目是 DTP的计划，以采购散装化学品和药物的治疗， 艾滋病与药物作用的研究。 该项目提供了获得几乎任何类型的化学品的手段 化合物和提供大量非常高纯度的 毒品 准备材料的数量将由 药品资源分支，NCI，将涉及各种各样的 化学结构。 许多准备工作将涉及多个步骤 序列和制备的所有材料将被充分表征。 溶解度和稳定性研究以及成本数据将在 请求过程中

The project is for the preparation of known chemicals and bulk drugs which are needed by the Program for clinical use. The compounds selected for preparation are not readily available in the quality or quantities required from the original supplier or on the open market. This project is part of the DTP's program to procure bulk chemicals and drugs for the treatment of AIDS and the study of drug action. This project provides the means to obtain nearly any type of chemical compound and the ability to provide large quantities of very high purity drugs. Assignments of materials for preparation will originate with the Pharmaceutical Resources Branch, NCI and will involve a wide variety of chemical structures. Many of the preparations will involve multi-step sequences and all materials prepared will be fully characterized. Solubility and stability studies and cost data will be provided upon request.