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DNA Repair State Machines

DNA Repair State Machines
DNA 修复状态机
批准号:
EP/X027406/1
负责人:
Mark Dillingham
金额:
$67.6万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2023
资助国家:
英国
项目状态:
未结题
起止时间:
2023 至 --
关键词:

项目摘要

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中文摘要
翻译
博士网络RepState旨在培养新一代生物化学和生物物理学领域的创新科学家,以解决有关关键DNA修复蛋白作为状态机的作用模式的生物学核心问题。RepState是一个高度协作的联盟,由来自学术界、工业界和创意部门的11名参与者组成,代表了自然科学和社会科学。参与RepState的实验室是知名研究机构和大学内已建立的研究学院的一部分。这个卓越的环境为10名年轻的研究人员提供了一个多学科的博士课程,通过生物学和人类健康基础化学和物理原理的培训。此外,培训将侧重于利用学术参与者以及两家小型技术驱动公司提供的技术和经验进行方法开发。培训包括当地项目、合作伙伴实验室的轮岗、接触非学术部门和年度会议。研究员将参加科学讲习班、可转移技能和职业发展课程,并将与创意部门密切合作,向不同的受众传播和交流他们的项目。RepState研究员将形成新一代成熟和创新的欧洲科学家,他们对生物学的基本定量原理有透彻的了解,在技术开发方面有经验,在多个部门有职业前景,并了解基础科学对社会和人类健康的重要性。
英文摘要
The Doctoral Network RepState aims to train a new generation of innovative scientists in biochemistry and biophysics to address central questions in biology concerning the mode of action of critical DNA Repair proteins that act as state machines. RepState consists of a highly collaborative consortium consisting of 11 participants coming from academia, industry and the creative sector, representing the natural sciences as well as the social sciences. Participating laboratories in RepState are part of established research schools within renowned research organizations and universities. This environment of excellence offers a multidisciplinary PhD program to 10 young researchers, through training in the fundamental chemical and physical principles that underlie biology and human health. In addition, training will focus on method development using technology and experience provided by the academic participants as well as by the two small technology-driven companies. Training incorporates a local program, rotations within partner laboratories, exposure to the non-academic sector and annual meetings. Fellows will follow scientific workshops, courses in transferable skills and career development, and will disseminate and communicate their projects to a diverse audience in close collaboration with the creative sector. The RepState fellows will form a new generation of mature and innovative European scientists with a thorough understanding of fundamental quantitative principles underlying biology, with experience in technique development, career perspectives in multiple sectors and an understanding of the importance of the role of fundamental science for society and human health.
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  • 项目类别:
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  • 资助金额:
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  • 财政年份:
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  • 资助金额:
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海外基金