SKIN DISEASE RESEARCH

埃默里皮肤病研究核心中心(ESDRC)将促进， 协调和加强24个临床和基础部门之间的协作 来自广泛研究学科的科学主义者。他们的专业知识 将侧重于皮肤病的机制以及皮肤 生物学，特别强调皮肤的作用 这些过程中的微血管构筑。这一强调将利用 一组杰出的、多学科的内皮细胞 生物学家，他们中的许多人以前从未将他们的专业知识集中在 皮肤。结合调查人员的专业知识和经验 在皮肤科，这组科学家集中在 ESDRC将对皮肤的作用提供新的见解 微血管内皮细胞在多种皮肤相关生物和 病理过程，包括急性和慢性炎症，伤口 愈合、血管生成、血管炎、卡波西肉瘤和肿瘤 转移。充分利用专业知识的多样性和现有的 埃默里研究中心和服务，ESDRC将被组织成 三大科学核心：1)组织培养和抗体生产 核心；2)微量化学成分；以及c)流式细胞术/细胞 分类部分；最后3)分析方法，多样性 对所有ESDRC调查人员和 研究员在他们的实验室里。因此，这些 设施将极大地提高参与的生产力 调查人员。此外，还进行了六项试点和可行性研究 从提交审查的13人小组中选出。他们都是 聚焦于真皮微血管细胞，并演示了一种 广泛的专业知识、技术和科学原理 目前一般用于皮肤生物学的研究， 尤其是真皮微血管。此外，一个 全面和多学科的丰富计划将提供 定期举办研讨会、研讨会和访问科学家演讲， 将极大地改善埃默里大学的研究和教育环境。 ESDRC的长期目标是提供新的见解和 皮肤病理生理过程的探讨 促进和协调多学科的研究方法 各种国家认可的调查人员及其实验室。

The Emory Skin Disease Research Core Center (ESDRC) will foster, coordinate and enhance collaborative efforts among 24 clinical and basic scientistic from a wide range of research disciplines. Their expertise will be focused on mechanisms of cutaneous disease as well as cutaneous biology, with special emphasis on the role of the cutaneous microvasculature in these processes. This emphasis will take advantage of an outstanding, multidisciplinary group of endothelial cell biologists, many of whom have never before focused their expertise on the skin. Combined with the expertise and experience of the investigators in the Department of Dermatology, this group of scientists centered at the ESDRC will provide novel insights into the role of cutaneous microvascular endothelial cells in a variety of skin-related biologic and pathologic processes, including acute and chronic inflammation, wound healing, angiogenesis, vasculitis, Kaposi's sarcoma, and tumor metastasis. Capitalizing upon the diversity of expertise and existing Emory research centers and services, the ESDRC will be organized into three scientific cores: 1) the Tissue Culture and Antibody Production Core; 2) the Microchemical Component; and c) a Flow Cytometry/Cell Sorting Component; and finally 3) the analytical approaches, a diversity of expertise, and continuous training for all ESDRC investigators and the research fellows in their laboratories. As a consequence, these facilities will greatly enhance the productivity of participating investigators. Additionally, six pilot and feasibility studies have been selected from a group of 13 submitted for review. All of them are focused on dermal microvascular cells and demonstrate application of a broad spectrum of expertise, techniques,and scientific rationale not currently being utilized in the study of cutaneous biology in general, and the dermal microvasculature in particular. Additionally, a comprehensive and multidisciplinary Enrichment Program will provide regular seminars, workshops, and visiting scientist presentations that will greatly enhance the research and educational environment at Emory. The long term goals of the ESDRC are to provide novel insights and approaches into cutaneous pathologic and physiologic processes through fostering and coordinating a multidisciplinary research approach among a variety of nationally recognized investigators and their laboratories.