GENERAL CLINICAL RESEARCH CENTER

这项赠款提案要求提供继续支持所需的资金。 中国人民大学医学院综合临床研究中心主任 北卡罗来纳大学教堂山分校。这个设施，曾经是 最早接受联邦支持的GCRC之一是 由美国国立卫生研究院连续资助30多年 好几年了。 北方大学临床研究中心的目标 卡罗莱纳在教堂山体现了已经制定的指导方针 由国家GCRC计划提供。这些是：a)创建最佳的 身体功能正常和异常的调查设置；b) 为人类的起源和自然历史提供一个设施 疾病可以被定义，疾病的进展、预防、 控制，并可研究治愈；c)便于快速翻译 将基础科学知识的进步转化为新的或改进的方法 用于病人护理；以及d)作为一个协调中心和机构 所有类型的卫生专业人员都可以接受培训的资源 临床调查的多个方面。 此应用程序包含临床研究的摘要，该研究具有 自1985年上次检讨以来，一直就这项研究进行检讨，然后 介绍未来五年的拟议研究活动 周而复始。此外，我们还比较详细地描述了 临床研究中心不仅向医学院，而且向 包括诺斯大学在内的整个研究社区 卡罗莱纳医院和卫生事务校园的所有五所学校 北卡罗来纳大学教堂山分校和这样的联邦大学 NIEHS和EPA等机构，这两个机构的位置都很接近 距离医疗中心很近。最后，我们在这方面强调了 应用不仅是在临床上进行的调查 GCRC，也是中心在教育和教育中发挥的重要作用 培训当前和未来的临床研究人员。

This grant proposal requests the funds necessary for continued support of the General Clinical Research Center of the School of Medicine of the University of North Carolina at Chapel Hill. This facility, which was one of the very earliest GCRCs to receive federal support, has been continuously funded by the National Institutes of Health for over 30 years. The goals of the Clinical Research Center of the University of North Carolina at Chapel Hill mirror the guidelines that have been set forth by the national GCRC program. These are: a) to create an optimal setting for investigation of both normal and abnormal body function; b) to provide a facility where the cause and the natural history of human illness can be defined and where disease progression, prevention, control, and cure can be studied; c) to facilitate the rapid translation of advances in basic scientific knowledge into new or improved methods for patient care; and d) to serve as a focal point and an institutional resource where health professionals of all types can receive training in the many aspects of clinical investigation. This application contains a summary of the clinical research that has been carried out on this GCRC since its last review in 1985, and then presents the proposed research activities for the upcoming five year cycle. In addition, we have described in some detail the importance of the Clinical Research Center not just to the School of Medicine, but to the entire research community that encompasses the University of North Carolina Hospitals and all five schools of the health affairs campus of the University of North Carolina at Chapel Hill and to such federal agencies as the NIEHS and the EPA, both of which are located in close proximity to the Medical Center. Finally, we have emphasized in this application not only the clinical investigation that takes place on the GCRC, but also the vital role played by the Center in the education and training of current and future clinical investigators.