LUMINOSA - LUminescent porphyrin Metal-organIc frameworks as oxygeN cOnsumption reporterS for bacteria-induced repair of concrete microcrAcks

及时干预修复混凝土裂缝对于防止大规模结构故障和避免随之而来的社会经济破坏至关重要。生物矿化最近成为当前劳动和时间密集型混凝土修复技术的替代方案，这种技术每年的支出高达40亿欧元。生物矿化利用了方解石的沉淀，这些方解石是由在混凝土中播种的细菌促进的，可以密封微裂缝，防止水渗透和裂缝扩展。这种方法可以提供自我修复的建筑材料，大大降低了混凝土结构维护的成本和碳足迹。生物矿化技术的发展是一项广泛应用的技术，它依赖于能够实时监测混凝土环境中细菌的生存情况，以保证可靠的方解石沉积以达到最佳修复。LUMINOSA项目旨在开发创新的光学传感器，通过绘制生物矿化处理过程中混凝土微裂缝中的耗氧量来评估细菌活力。我们将合成一个含羧基的氧响应铂卟啉文库（目标1）。我们将在金属有机框架（mof）中加入这些物种，以提供在水环境中具有增强响应的发光传感器（Obj 2）。我们将利用mof的氧响应性来可视化/绘制混凝土微裂缝中具有生物矿化能力的细菌种群的耗氧量（实验3）。该项目的成功交付将扩大光学传感在生物矿化中的适用性，深化特定领域的知识，并使具有高影响力的技术具有社会效益。这个高度跨学科的项目旨在通过建立广泛的研究组合，创造机会建立独立的跨部门网络，加强跟踪记录和扩大研究特定和可转移的技能，从而提高学术生涯的前景。

Prompt intervention to repair cracks in concrete is crucial to prevent large-scale structural failures and avert consequent socioeconomic disruptions. Biomineralization recently emerged as an alternative to the current labour- and time-intensive concrete repair techniques, which cause a staggering 4-6 billion Eur yearly expenditure. Biomineralization exploits calcite precipitation promoted by bacteria seeded in concrete, sealing microcracks and preventing water penetration and fracture expansion. This approach can afford self-healing construction materials that drastically reduce the cost and carbon footprint of concrete structures maintenance. Development of biomineralization into a widely applied technique relies on the ability to monitor bacteria survival in concrete environment in real time, to guarantee reliable calcite deposition for optimal repair. The LUMINOSA project aims at developing innovative optical sensors to assess bacteria viability by mapping oxygen consumption in concrete microcracks during biomineralization treatment. We will synthesise a library of oxygen-responsive platinum porphyrins bearing carboxylic groups (Obj 1).We will incorporate these species in metal organic frameworks (MOFs) to afford luminescent sensors with enhanced response in aqueous environment (Obj 2). We will exploit the oxygen responsiveness of the MOFs to visualise/map oxygen consumption by biomineralization-capable bacteria populations in concrete microcracks (Obj 3). Successful delivery of this project will widen the applicability of optical sensing in biomineralization, deepening field-specific knowledge and enabling a high-impacting technology for societal benefit. This highly interdisciplinary project is tailored to enhance the prospect of academic career through building a broad research portfolio, generating opportunities to forge independent intersectoral networks, strengthening track record and expanding research specific and transferrable skills.