Cross Presentation and tumour immunology
Cross Presentation and tumour immunology
批准号:
nhmrc : 1029589
负责人:
Prof Anna Nowak
金额:
$29.68万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2015-12-31
中文摘要
癌症有成千上万的突变,所以它们看起来有点像病毒感染。如果是这样的话,为什么免疫系统不像消灭病毒那样直接消灭它们呢?我们认为突变的蛋白质会导致抗癌免疫反应的“刹车”,并且癌症通过隐藏在目标区域中来破坏抗癌攻击。打开这些“刹车”可能会带来新的治疗方法。
英文摘要
Cancers have thousands of mutations, so they should look a bit like a viral infection. If so, why doesn’t the immune system just destroy them outright, like they would a virus? We think the mutated proteins cause a ‘brake’ to be put on the anti-cancer immune response, and also that cancers subvert the anti-cancer attack by remaining hidden in the target zone. Unblocking these “brakes” might lead to new treatments.
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会议论文
Improving treatment outcomes for malignant mesothelioma patients using biomarkers.
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批准号:nhmrc : 1063067
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项目类别:Project Grants
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资助金额:$53.03万
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财政年份:2014
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负责人:Prof Anna Nowak
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依托单位:
Can biomarkers improve outcomes for the asbestos-induced cancer malignant mesothelioma?
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批准号:nhmrc : GNT1063067
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项目类别:Project Grants
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资助金额:$51.28万
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财政年份:2014
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负责人:Prof Anna Nowak
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依托单位:
National Centre for Asbestos Related Diseases
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批准号:nhmrc : 1001020
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项目类别:Centres of Research Excellence
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资助金额:$341.4万
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财政年份:2010
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负责人:Prof Anna Nowak
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依托单位:
海外基金