RDOG IV--HEADQUARTERS AND STATISTICAL CENTER

该应用程序响应了运营/数据管理的需求， RFA 92-CA-02的统计中心将成为 放射诊断肿瘤组（RDOG）。 拟议 中心将继续设在美国放射学院 和哈佛医学院。 本申请要求 继续支持多项任务。 主要包括以下内容：1） 支持调查人员设计、开发和实施 新的协议; 2）在设计，开发和 数据收集机制的实施; 3）持续监测 并验证图像质量、方案合规性和数据完整性; 4） 设计和执行数据的统计分析，并生成 （5）解决在研究中出现的方法问题， 设计和分析协作成像研究。 我们还将 参与编写摘要和手稿， 方案发现。 在这些中心和 参与RFA 92-CA-02的机构，我们将扩大我们的研究 给两类重要的病人，儿童和妇女。

This application responds to the need for Operations/Data Management and Statistical Centers for RFA 92-CA-02 that will become part of the on-going Radiological Diagnostic Oncology Group (RDOG). The proposed centers will continue to be based at the American College of Radiology and Harvard Medical School respectively. This application requests continued support for several tasks. Key ones include the following: 1) to support investigators in the design, development and implementation of new protocols; 2) to work with them in the design, development and implementation of data collection mechanisms; 3) to continually monitor and verify image quality, protocol compliance and data completeness; 4) to design and perform statistical analyses of the data and to generate relevant reports; and 5) to address methodologic issues arising in the design and analysis of collaborative imaging studies. We will also participate in the preparation of abstracts and manuscripts based on protocol findings. With the support of these centers and the institutions participating in RFA 92-CA-02, we will extend our research to two important classes of patients, children and women.