BLOOD STORAGE PATTERNS AND RED CELL CONTAMINATION BY YERSINIA ENTEROCOLITICA

最近向疾控中心提交的报告记录了10例感染性休克病例， 包括7人死于输血红细胞(RBC) 被小肠结肠炎耶尔森氏菌污染。这些事件与 单位使用时间超过25天。减少约会的可能性 储存RBC的期限为25天被认为是一种潜在的手段 减少受污染单位输血的风险。为了获得 关于这一变化对血液供应的预期影响的信息，a Y.血液储存模式和红细胞污染的调查问卷。 年向所有登记的血液机构分发了小肠结肠炎。 1991年3月。数据是从大约1600份血液中获得的 机构，包括几乎所有参与的主要组织 采集和分发血液。将所有中心和所有约会结合在一起 储存单位的期间，约占#年全国库存的20% 红细胞被发现超过了28天的储存，这表明了一种严重的错位 如果约会时间缩短的话。仅有一例新的不良反应病例 对小肠结肠炎耶尔森氏菌的反应被鉴定，表明 之前的报道。这些数据有助于血盟做出决定 产品咨询委员会，1991年5月，不建议减少约会 用于冰箱储存的红细胞。

Recent reports to the CDC have documented ten cases of septic shock, including seven deaths, due to red blood cell (rbc) transfusions contaminated with Yersinia enterocolitica. These incidents were associated with units older than 25 days. The possibility of reducing the dating period to 25 days for stored rbc was considered as a potential means for reducing the risk of transfusion of a contaminated unit. To obtain information on the expected impact on the blood supply of such a change, a questionnaire on blood storage patterns and rbc contamination by Y. enterocolitica was distributed to all registered blood establishments in March, 1991. Data were obtained from approximately 1600 blood establishments including virtually all the major organizations engaged in blood collection and distribution. Combining all centers and all dating periods for stored units, approximately 20% of the national inventory of rbc was found to exceed 28 days of storage, suggesting a major dislocation if the dating period were to be reduced. Only a single new case of adverse reaction to Y. enterocolitica was identified, indicating the adequacy of prior reporting. These data contributed to a decision by the Blood Products Advisory Committee, in May, 1991, not to recommend reduced dating for refrigerator stored rbc.