THE EFFECT OF EARLY VERSUS LATE ONSET OF CHILDHOOD ASTHMA

关于儿童哮喘发病年龄的作用还存在争议 哮喘。收集自我报告的医生诊断为哮喘患者的数据 参加第二次全国健康调查的376名6~24岁儿童 和营养检查，1976-1980年，全国横断面 样本，检查是否预测发病在2岁或之前 未来的路线。早发性哮喘患者往往更有可能患上 曾因胸部疾病住院过，优势比(OR)=2.3(95% CI 0.7，6.8)，有慢性痰浊(OR=1.6(95%CI 0.8， 3.4)，男性OR=1.7(95%CI 1.0，2.7)。迟发性哮喘患者倾向于 要报告更多过敏性鼻炎(OR=1.5(95%CI 0.8，2.9)，请在 至少一项刺激性变应原皮肤试验阳性(R=1.5(95%可信区间 0.7，3.3)，报告身体良好或非常好(R=1.2，3.7)，为白人 OR=2.2(95%CI 1.1，4.2)，居住在市区OR=2(95%CI 1.1， 3.7)，家庭收入低于贫困OR=1.6(95%可信区间1.1，2.5)。不是 在报告的慢性鼻炎、是否曾去MD就诊方面发现了差异 对于胸部状况，报告哮喘处于活动状态， 在过去的12个月里，他有喘息，咳嗽，或缺课。这个 社会人口学和过敏特征因发病年龄而异， 但最近的严重程度并非如此。

Controversy exists as to the role of age of asthma onset in childhood asthma. Data collected on self-reported physician-diagnosed asthmatics ages 6-24 yrs (N=376), who participated in the second National Health and Nutritional Examination, 1976-1980, a national cross-sectional sample, were examined to see if onset at or before age 2 years predicted future course. Early onset asthmatics tended to be more likely to have been ever hospitalized for a chest condition odds ratio (OR) = 2.3 (95% CI 0.7, 6.8), have chronic problems with phlegm (OR = 1.6 (95% CI 0.8, 3.4), be male OR = 1.7 (95% CI 1.0, 2.7). Late onset asthmatics tended to report more allergic rhinitis (OR = 1.5 (95% CI 0.8, 2.9), have at least one positiveprick-puncture allergen skin test (R = 1.5 (95% CI 0.7, 3.3), report excellent or very good health (R = 1.2, 3.7), be white OR = 2.2 (95% CI 1.1, 4.2), live in an urban area OR = 2 (95% CI 1.1, 3.7), have family incomes below poverty OR = 1.6 (95% CI 1.1, 2.5). No difference was found for reported chronic rhinitis, ever visiting an MD for chest condition, reporting asthma to be active, problems within the last 12 months with wheezing, cough attacks, or missing school. The sociodemographic and allergic characteristics varied by age of onset, but recent severity did not.