MONOCLONAL ANTIBODIES TO DETECT OCCULT CARCINOMA CELLS

单抗(MAb)已被用于 (A)隐匿性疾病检测的免疫组织化学方法 外科和细胞学准备中的癌，(B)表型 恶性细胞群，(C)组织分化 肿瘤类型，以及(D)各种细胞产品的鉴定。 对肿瘤相关抗原具有选择性反应的单抗 已被特别改装用于细胞学制剂 包括细胞旋体、膜和细针抽吸 活检(FNAB)用于检测和鉴别 来自良性细胞类型和其他癌性病变的癌。

Monoclonal antibodies (Mabs) have been utilized with immunohistochemical methods for the (a) detection of occult carcinoma in surgical and cytology preparations, (b) phenotyping of malignant cell populations, (c) differentiation of histologic tumor types, and (d) identification of various cellular products. Mabs with selective reactivity against tumor-associated antigens have specifically been adapted for use with cytologic preparations including cytospins, membranes, and fine needle aspiration biopsies (FNAB) for the detection and differentiation of carcinomas from benign cell types and other cancerous lesions.