GENERAL CLINICAL RESEARCH CENTER

这是一项建立综合临床研究中心(GCRC)的建议 鲍曼·格雷医学院(BGSM)/北卡罗来纳州浸信会 NCBH医院医疗中心。GCRC旨在：1)促进， 通过开展支持和提高生物医学研究的卓越水平 高效和多产的临床研究；2)提供核心 在此基础上开展研究计划和教育活动 和加强；3)进一步促进医者之间的互动 科学家和基础科学家；4)提供激励初级科学家的重点 教职员工以及学生、房屋工作人员和受训人员，以 将创造性的临床研究纳入他们的职业目标；以及5)服务 作为临床研究培训的教育资源。GCRC 物理设施位于战略位置，将由住院患者组成 床位、门诊检查室、程序室、核心实验室、 代谢厨房、护士站、会议室、计算机室和 项目主任、副主任、管理员和负责人的办公室 护士。该中心很容易被门诊患者进入，而且很近 距离其他医院单元很近。GCRC将由以下机构联合运营 BGSM和NCBH基于相互承诺和责任；它 将适用于医疗中心的所有学科。首字母 临床调查涉及内科， 神经学、外科、儿科学、麻醉学、公共卫生科学、 生物化学、微生物学和免疫学。这项研究还涉及 机构内的跨学科方案努力： 维克森林大学综合癌症中心动脉粥样硬化 SCOR计划，卒中中心，分子遗传学计划， 炎症生物学项目和J.Paul Sticht中心 衰老。研究主题包括：内分泌代谢、心脏病学、 肿瘤学、肺部和重症监护医学、传染病、 胃肠病、肌肉骨骼疾病、血管外科和 流行病学。临床科学和医学之间存在着合作 微生物学和免疫学、生物化学和分子基础科学 遗传学。在成立50周年之际，该机构准备建立 GCRC的基础是：1)临床数量和质量的提高 在该机构进行研究；2)BGSM/NCBH医学中心作为 生物医学研究和患者护理中心；3) 部门和方案研究工作；以及4)增加 基础科学与临床合作项目的数量 教职员工。建立GCRC是培养更多学术人才的关键 在这个医疗中心成熟，并在20世纪90年代发起这个GCRC 将允许，从头开始，开发一种基本的临床- 适合新兴市场的基于人口的协作研究 21世纪的生物医学科学。

This is a proposal to establish a General Clinical Research Center (GCRC) at the Bowman Gray School of Medicine (BGSM)/North Carolina Baptist Hospital (NCBH) Medical Center. The GCRC is designed to: 1) promote, support, and enhance excellence in biomedical research through the conduct of efficient and productive clinical investigations; 2) provide a nucleus upon which research programs and educational activities can be developed and strengthened; 3) further facilitate interactions between physician scientists and basic scientists; 4) provide a focus which stimulates junior faculty, as well as students, house staff, and fellows-in-training, to include creative clinical research in their career objectives; and 5) serve as an educational resource for training in clinical research. The GCRC physical facility is strategically located and will consist of inpatient beds, outpatient examining rooms, procedure room, core laboratory, metabolic kitchen, nurses' station, conference room, computer room, and offices for program director, associate director, administrator, and head nurse. The center is easily accessed by outpatients, and it is in close proximity to other hospital units. The GCRC will be jointly operated by the BGSM and the NCBH based on mutual commitments and responsibilities; it will be available to all disciplines in the medical center. The initial clinical investigations involve the Departments of Internal Medicine, Neurology, Surgery, Pediatrics, Anesthesiology, Public Health Sciences, Biochemistry, and Microbiology and Immunology. The research also involves interdisciplinary programmatic efforts within the institution: the Comprehensive Cancer Center of Wake Forest University, the Atherosclerosis SCOR Program, the Stroke Center, the Program in Molecular Genetics, the Program on the Biology of Inflammation, and the J. Paul Sticht Center on Aging. Research themes include: endocrine-metabolism, cardiology, oncology, pulmonary and critical care medicine, infectious diseases, gastroenterology, musculoskeletal disease, vascular surgery, and epidemiology . Collaborations exist between clinical sciences and the basic sciences of microbiology and immunology, biochemistry, and molecular genetics. At its 50th anniversary, the institution is poised to establish a GCRC based on: 1) increases in the quantity and quality of clinical research at the institution; 2) growth of the BGSM/NCBH Medical Center as a biomedical research and patient care center; 3) close interactions among departmental and programmatic research efforts; and 4) increases in the number of collaborative programs between basic science and clinical faculty. Establishment of a GCRC is critical to fostering further academic maturation at this medical center, and initiating this GCRC in the 1990s will allow the development, de novo, of a model of basic clinical- population-based collaborative research appropriate to the emerging biomedical sciences of the 21st century.