RENAL PHOSPHATE HANDLING AND BONE DENSITY IN CHILDHOOD CHOLESTASIS

已观察到甲状旁腺激素非依赖性肾磷酸盐消耗 慢性胆汁淤积性肝病的儿童。 之间的相关性 这种来自磷酸盐池和骨密度的损失是假设的。 年龄 肾磷酸盐处理和骨密度的适当对照组 (dual光子吸收测定法）。 儿童数据 长期胆汁淤积和儿童吸收不良，由于其他 原因（例如，囊性纤维化）与对照数据进行比较。

Parathyroid hormone independent renal phosphate wasting has been observed in children with chronic cholestatic liver disease. A correlation between this loss from the phosphate pool and bone density is hypothesized. Age appropriate control groups for renal phosphate handling and bone density (dual photon absorptiometry) will be established. Data from children with protracted cholestasis and from children with malabsorption due to other causes (e.g., cystic fibrosis) can then be compared to the control data.