Defining Stromal-Cancer Cell Interactions for Xenografting Human Prostate Cancer

前列腺癌研究继续受到缺乏实验室模型的阻碍，以了解疾病的进展和设计新药来治愈这种疾病。在这项研究中，我们建议使用一种新的和可靠的方法在小鼠中生长人前列腺癌组织。使用这个模型，我们将研究激素信号传导和细胞通讯在前列腺癌中的作用，这可能会为被诊断患有器官局限性疾病的男性带来新的治疗方法。

Prostate Cancer research continues to be hindered by a lack of laboratory models to understand disease progression and design new drugs to cure the disease. In this study, we propose to use a new and reliable method of growing human prostate cancer tissue in mice. Using this model, we will investigate the role of hormone signalling and cellular communication in prostate cancer that may lead to new therapies for men diagnosed with organ-confined disease.