TREATMENT OF MALIGNANT BRAIN TUMORS WITH INTERSTITIAL RADIOTHERAPY

高级别胶质瘤的中位生存期仍不到一年 尽管进行了多种形式的治疗 治疗被认为是轶事。 这些肿瘤通常已经超出了一个 完整的手术切除和一剂常规的外用 放射治疗受到周围脑组织的限制， 宽容 我们相信我们可以达到更高的辐射 通过放置放射性碘125种子对肿瘤进行剂量治疗 直接进入肿瘤床，辐射急剧下降， 周围正常的大脑。 希望这将实现一个很大的 更好的治疗比，特别是在低剂量给药时 rates.

Median survival of high-grade gliomas remains less than a year despite multi-modality treatment. Cure is considered anecdotal. These tumors usually have extended beyond the limits of a complete surgical resection and a dose of conventional external beam radiotherapy has been limited by surrounding brain tolerance. We believe that we can achieve a higher radiation dose to the tumor by placing radioactive seeds of Iodine 125 directly into the tumor bed, with a sharp fall-off of radiation to the surrounding normal brain. Hopefully this will achieve a much better therapeutic ratio, especially when delivered at low dose rates.