UPDATES FOR MICROCHEMICAL FACILITY

怀俄明州大学的微量化学设施已经 已经运营三年了 目前提供的服务 包括：1）蛋白质-肽测序，2）氨基酸分析 水解和生理液体，3）DNA合成，和4） 肽合成 测序和氨基酸分析 服务已被12个校园调查员在四个 部门和20名校外调查人员， 许多其他机构。 效率的关键因素 这个实验室的生产力一直是技术和 两个运营商的奉献精神。 然而，很明显，他们的 能力已经达到，解决持续的 该设施的最佳操作是更新测序仪， 包括自动在线PTH分析仪， 自动化、灵活的化学氨基酸分析仪。 那些是 本提案中要求的项目。 有四个主要用户和一个 校园内外都有大量的未成年人用户。

The Microchemical facility at the University of Wyoming has been operating for three years now. Services available currently include: 1) protein-peptide sequencing, 2) amino acid analyses both hydrolysis and physiologic fluid, 3) DNA synthesis, and 4) peptide synthesis. The sequencing and amino acid analysis services have been used by twelve on-campus investigators in four departments and by twenty off-campus investigators from numerous other institutions. A critical factor in the efficiency and productivity of this laboratory has been the skill and dedication of the two operators. However, it is clear that their capacity has been reached and the solution to the continued optimal operation of this facility is to update the sequencers to include the automated on-line PTH analyzes and to have an automated, flexible chemistry amino acid analyzer. Those are the items requested in this proposal. There are four major users and a large number of minor users both on- and off-campus.