CLINICAL RESEARCH CENTER FOR NEUROMUSCLAR DISEASE

这个跨学科项目的广泛目标是阐明 人类神经肌肉疾病的发病机制。 该中心由17个 13个实验室的独立调查员。 在许多项目中， 科学家和临床研究人员一起工作。 基础研究 包括肌肉激活和收缩的动力学，钙 肌肉调节，人体肌纤维生理学，肌纤维超微结构 肌肉，肌肉发育，肌肉培养免疫细胞化学， 乙酰胆碱受体的结构和功能。 临床研究包括肌营养不良症、肌无力 重症、恶性高热、糖原和脂质代谢紊乱， 氨基己糖苷酶缺乏和周围神经病。

The broad objective of this interdisciplinary project is to elucidate the pathogenesis of human neuromuscular diseases. The Center comprises 17 independent investigators in 13 laboratories. In many projects basic scientists and clinical investigators work together. Basic research includes the dynamics of muscle activation and contraction, calcium regulation in muscle, physiology of human muscle fibers, ultrastructure of muscle, development of muscle, muscle culture immunocytochemistry, glycoconjugates, structure and function of acetylcholine receptor. Clinical investigation includes study of muscular dystrophy, myasthenia gravis, malignant hyperthermia, disorders of glycogen and lipid metabolism, hexosaminidase deficiency, and peripheral neuropathy.