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Bipolar -II Disorder

Bipolar -II Disorder
双相-II型障碍
批准号:
G0800621/1
负责人:
Nicol Ferrier
金额:
$83.23万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2009
资助国家:
英国
项目状态:
已结题
起止时间:
2009 至 --
关键词:

项目摘要

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中文摘要
翻译
双相情感障碍(也称为躁郁症)是一种常见的金属健康问题,大约每50人中就有1人受到影响。实际上有两种类型的双相障碍:双相I型障碍和双相II型障碍:双相I型障碍是经典描述的躁狂抑郁形式,伴随着兴高采烈和抑郁的时期。关于这种形式的双相情感障碍和可能在短期和长期都有帮助的最佳治疗选择的研究很多,而且还在不断增加。近年来,双相障碍的第二种形式--双相II型障碍实际上更为常见,尽管?(躁狂症状)没有躁郁症那么严重,抑郁症的症状比双相I型障碍更持久和更致残。不幸的是,双相II型障碍几乎从来都不是研究的主要焦点,因此我们对问题如何随着时间的推移发展的了解存在重大差距,我们不清楚最佳治疗方案。该项目建议寻求180名双相II型障碍患者在医院和初级保健服务中的合作。例如,我们将使用自我评分日记来研究这个问题的自然过程,并通过邀请参与该项目的人参加小型治疗试验,为他们提供接受新药或心理治疗的机会。参与者及其照顾者将积极参与决定哪些研究是最重要的,以改善患者及其家人的生活质量。此外,个人和他们的家人将有机会参加关于双相II型障碍的介绍性讲座,让每个人都分享关于这个问题的信息。研究人员还将举办一系列讲座,让参与研究的人了解该项目的最新发现。
英文摘要
Bipolar Disorder (also called Manic Depression) is a common metal health problem that affects about 1 in 50 persons. There are actually two types of Bipolar Disorder: Bipolar I disorder and Bipolar II disorder: Bipolar I disorder is the classically described form of manic depression with periods of elation and depression. There is a large and growing body of research on this form of Bipolar Disorder and the best treatment options that may help in both the short-term and longer-term. In recent years it has become apparent that the second form of Bipolar Disorder, Bipolar II disorder is actually more common and, although the ?highs? (symptoms of mania) are less severe, the symptoms of depression are more persistent and disabling than in Bipolar I disorder. Unfortunately, Bipolar II disorder is hardly ever the main focus of research studies and so there are major gaps in our knowledge of how the problem develops over time and we are unclear about the best treatment options. This project proposes to seek the collaboration of 180 individuals with Bipolar II disorder attending both hospital and primary care services. We will study the natural course of this problem using e.g. self-rated diaries, as well as offering people involved in the project the opportunity to receive new medications or psychological treatments by inviting them to take part in small treatment trials. Participants and their carers will play an active part in deciding which studies are the most important to undertake in order to improve the quality of life for patients and their families. Also individuals and their families will be offered the opportunity to attend introductory talks about Bipolar II disorders to let everyone share information about this problem. A series of talks by the researchers will also be offered to keep people involved in the studies up to date with the findings of the project.
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  • 批准号:
    2026JJ30126
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2026
  • 负责人:
    杨沙
  • 依托单位:
苏合颗粒治疗慢性萎缩性胃炎的临床(II期)评价关键技术研究