Development of Adoptive immunotherapy of EBV-associated Malignancies by Retroviral LMP2-TCR Gene Transfer
Development of Adoptive immunotherapy of EBV-associated Malignancies by Retroviral LMP2-TCR Gene Transfer
批准号:
G0902209/1
负责人:
Hans Stauss
金额:
$35.45万
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2010
资助国家:
英国
项目状态:
已结题
起止时间:
2010 至 --
中文摘要
爱泼斯坦巴尔病毒(EBV)可导致几种不同类型的癌症。目前还没有治疗这些癌症的方法。我们的建议是从EBV相关癌症患者身上提取血细胞,将其转化为针对癌细胞的杀伤细胞,然后再注射回患者体内。这些杀伤细胞将能够摧毁癌细胞并治愈患者。
英文摘要
Epstein Barr Virus (EBV) can cause several different types of cancer. There are currently no treatments available for some of these cancers. Our proposal is to take blood cells from patients with EBV-associated cancer and turn them into killer cells directed towards the cancer cells and then inject back into the patient. These killer cells will then be able to destroy the cancer cells and cure the patient.
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会议论文
Antigen-specific co-stimulation to enhance the anti-tumour activity of TCR gene modified cytotoxic T lymphocytes
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批准号:G0700149/1
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项目类别:Research Grant
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资助金额:$42.95万
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财政年份:2008
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负责人:Hans Stauss
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依托单位:
海外基金