BIOLOGY AND EXPERIMENTAL THERAPY OF BREAST CANCER

包括在这个计划的项目侧重于自然历史，因果关系， 实体瘤的检测和实验性治疗，强调使用 化疗药物和免疫及内分泌系统的调节剂。 乳腺和胰腺肿瘤的临床试验：病因、早期发现和 膀胱肿瘤的膀胱内治疗;骨转移分析; 乳腺癌和前列腺癌中的高钙血症：体外和临床 左旋咪唑和干扰素的免疫学作用;药理学和 含铂配合物的临床疗效， 抗雌激素药物包括正在进行的研究。 该计划依赖于实验室和 临床研究者、生物统计学家和数据管理专家， 一个综合的、互动的努力。

Projects included in this program focus on the natural history, causation, detection, and experimental treatment of solid tumors, stressing use of chemotherapeutic drugs and modulators of the immune and endocrine systems. Clinical trials for breast and pancreatic tumors; causation, early detection and intravesical treatment of bladder tumors; analysis of bony metastasis and hypercalcemia in breast and prostate cancers; in vitro and clinical immunological effects of levamisole and interferon; and pharmacology and clinical efficacy of platinum-containing coordination compounds and antiestrogens comprise studies under way. The program depends on interdisciplinary collaboration of laboratory and clinical investigators, biostatisticians, and data management experts devoted to an integrated, interactive effort.