课题基金 / 基金详情

ABNORMALITIES IN HYPOTHALAMIC/PITUITARY/OVARIAN AXIS IN IDDM WOMEN

ABNORMALITIES IN HYPOTHALAMIC/PITUITARY/OVARIAN AXIS IN IDDM WOMEN
IDDM 女性下丘脑/垂体/卵巢轴异常
批准号：
5225665
负责人：
JAMES H. LIU
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5225665
关键词：
clinical research diabetes mellitus therapy female gestational diabetes mellitus gonadotropin releasing factor human subject human therapy evaluation hypothalamic pituitary axis insulin dependent diabetes mellitus ovary disorder pituitary gonadal axis

项目摘要

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相关文献

中文摘要
翻译
初步证据表明促性腺激素缺乏。 下丘脑-垂体释放激素(GnRH)和黄体生成素(LH) 胰岛素依赖型糖尿病患者的脑室隔。这样做的目的是 该项目是为了测试纠正慢性病的假设 高血糖会导致内源性GnRH分泌正常化， 垂体促性腺激素分泌的恢复和矫治 生育年龄女性糖尿病患者的排卵异常 怀孕了。我们假设在建立正常血糖状态之前 受孕将改善生育结果。
英文摘要
Preliminary evidence suggests that there is a deficiency in gonadotropin releasing hormones (GnRH) and LH output from the hypothalamus pituitary compartment in women with insulin-dependent diabetes. The goal of this project is to test the hypothesis that correction of chronic hyperglycemia will lead to normalization of endogenous GnRH secretion, restoration of pituitary gonadotropin secretion and correction of ovulatory abnormalities in reproductive aged women diabetics desiring pregnancy. We postulate that establishment of a euglycemic state prior to conception will improve reproductive outcome.
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ANTIOXIDANT POTENTIAL OF ESTROGENS IN MENOPAUSE
ANTIOXIDANT POTENTIAL OF ESTROGENS IN MENOPAUSE
ABNORMALITIES IN HYPOTHALAMIC/PITUITARY/OVARIAN AXIS IN IDDM WOMEN
CLIN CTR CLIN TRIAL/OBSERVATIONAL STUDY OF WHI
  • 批准号：
    2326781
  • 项目类别：
  • 资助金额：
    $139.15万
  • 财政年份：
    1994
  • 负责人：
    JAMES H. LIU
  • 依托单位：
    UNIVERSITY OF CINCINNATI