BEHAVIORAL INTERVENTIONS FOR CONTROL OF TUBERCULOSIS

描述：该项目的总体目标是比较替代方案 确保完成结核病治疗和预防治疗的方法 ，并找出最具成本效益的方法来 做到这一点。比较的基础包括依从率和 作为主要结果的成本节约，以及其他参数，如患者 满意度、社交网络的发展和参与 将支持计划作为次要结果。两项临床试验是 建议对来自哈莱姆区的患者进行。在那些有 活动性疾病，以诊所为基础的代孕家庭模式将进行比较 转向传统的社区直接观察疗法(DOT)。其中 那些有资格接受预防性治疗的人，一种基于社区的干预 由受过培训的结核病DOT计划毕业生(同行工作人员)指导 可与传统的自我给药预防性治疗相比较。

DESCRIPTION: The overall aims of the project are to compare alternative methods to ensure completion of treatment and preventive therapy for TB in inner cities, and to identify the most cost-effective methods to accomplish that. The basis for comparison includes adherence rates and cost savings as primary outcomes, and other parameters such as patient satisfaction, development of social networks, and participation in support programs as secondary outcomes. Two clinical trials are proposed to be conducted with patients from Harlem. Among those with active disease, a clinic-based surrogate family model will be compared to traditional community-based directly observed therapy (DOT). Among those eligible for preventive therapy, a community-based intervention conducted by trained graduates of a TB DOT program (peer workers) will be compared to traditional self-administered preventive treatment.