Core--Cohort Facility

招募和保留研究对象是研究中最困难的组成部分之一。在处理诸如市中心、少数民族青少年等易受伤害和难以接触的人群时，这一困难更加严重。招募和保留研究对象可能既费力又费时，如果做得不好，可能会阻碍研究人员回答关键科学问题的能力。队列核心的总体目标是提供后勤支持，以招募、同意、筛选、登记和保留研究对象，并收集旧金山青少年和性传播疾病儿童基金会(SFCRC)所有项目所需的适当访谈和生物数据。该核心的目标是提供一切必要的支持，以确保SFCRC的各个项目获得实现其具体目标所需的数据。由于将以有组织的方式确定和招募个人，因此可以进行多项研究，而不会在社区内造成混乱。集中征聘模式允许同时实施若干研究以及今后扩大项目，而不会影响为开展初始项目而建立的渠道、意识和可接受性。具体来说，这个队列核心的目的是：1.招募、同意、筛选和登记通过随机数字拨号确定的目标人群中的青少年指数受试者的随机家庭概率样本9项目1、2、3)2.招募、同意并登记两代青少年指数受试者的性伴侣(项目1、3)3.招募、同意、筛选和登记性经验不足的女性青少年指标受试者的女性社会伴侣(项目2、3)。4.跟踪和保留研究对象以进行后续工作(项目1、2、3)5.确保成功收集访问数据和研究对象的生物标本(项目1、2、3)

Recruitment and retention of study subjects is one of the most difficult components of research. This difficulty is compounded when dealing with vulnerable and hard-to-reach populations such as inner-city, minority adolescents. Recruitment and retention of study subjects can be both labor- and time-intensive and if not done properly can impede researchers' ability to answer critical scientific questions. The overall objective of the Cohort Core is to provide the logistical support to recruit, consent, screen, enroll and retain study subjects and to collect the appropriate interview and biological data as needed for all projects of the San Francisco Adolescents and STDs CRC (SFCRC). It is the goal of this Core to provide all necessary support to ensure that the individual projects of the SFCRC receive the data needed to achieve their specific aims. Because individuals will be identified and recruited in an organized manner, multiple studies can be ongoing without creating confusion within the community. A centralized recruitment model allows for the implementation of several studies simultaneously as well as for future expansion of projects without jeopardizing the access, aware and acceptability established to conduct the initial projects. Specifically, the aims of this Cohort Core are to: 1. Recruit, consent, screen, and enroll a random household probability sample of adolescent index subjects from the target population identified through random-digit dialing 9Projects 1, 2, 3) 2. Recruit, consent, and enroll two generations of adolescent index subjects' sex partners (Projects 1, 3) 3. Recruit, consent, screen, and enroll female social partners of sexually inexperienced female adolescent index subjects (Projects 2, 3). 4. Track and retain study subjects for follow-up (Projects 1, 2, 3) 5. Ensure successful collection of interview data and biological specimens from study subjects (Projects 1, 2, 3)