SOLID STATE DETECTOR FOR GAS CHROMATOGRAPHY

使用放射性标记化合物的毛细管柱气相色谱是一种 分析化学中的重要工具，但它的性能，特别是 对于低能量的β粒子，受到辐射探测器的限制 它们都是目前使用的。我们建议开发一个基于Solid的系统 状态传感器将提供极高的灵敏度，而无需 妥协的解决方案。我们将使用雪崩来实现这一点 光电二极管(APD)，它已经证明了检测低电平的能力 能量β粒子，包括那些来自氚的粒子，具有高效率。 雪崩探测器是一种更好的辐射传感器，因为它可以用 一个非常薄的前窗口，具有内部增益，以提供非常高的 信噪比。此外，APD结构紧凑，允许良好的 在毛细管柱气相色谱中的分辨率，可在 阵列，对小样本具有非常高的灵敏度。 第一阶段的研究已圆满完成，所有 达到了技术目标。第一阶段演示了APDS可以 制造的效率超过任何其他固态材料 探测器。在第二阶段，研究将继续并扩大到 包括制造适合于 并入气相色谱仪器。

Capillary column gas chromatography using radiolabelled compounds is an important tool in analytical chemistry, but its performance, especially with low energy beta particles, is limited by the radiation detectors which are currently used. We propose to develop a system based on solid state sensors which will provide extremely high sensitivity without compromising resolution. We will accomplish this using avalanche photodiodes (APDs), which have demonstrated the ability to detect low energy beta particles, including those from tritium, with high efficiency. An APD is a superior sensor for such radiation because it can be made with a very thin front window and has internal gain to provide a very high signal-to-noise ratio. Moreover, APDs are compact, allowing good resolution in capillary column gas chromatography and can be made in arrays, allowing very high sensitivity for small samples. The research in Phase I was completed successfully and all of the technical goals were met. Phase I demonstrated that APDs could be fabricated with efficiencies exceeding those of any other solid state detector. In Phase II, the research will be continued and expanded to include the fabrication of complete detector systems suitable for incorporation into gas chromatography instruments.