Development and immunogenicity testing of

这项研究将推动基于鸭乙肝病毒样颗粒(VLP)的新型疫苗策略的开发。这些VLP可以被改造成含有部分其他病毒，如丙型肝炎、艾滋病毒或麻疹，并已被证明在小鼠身上产生强烈的抗体反应。有关这些VLP疫苗的细胞和抗体反应的详细信息将与GLP程序保持一致，以支持未来的人类临床试验，为开发针对一系列传染病的迫切需要的疫苗提供支持。

This research will advance the development of a novel vaccine strategy based on duck hepatitis B virus-like particles (VLPs). These VLPs can be engineered to contain parts of other viruses such as Hepatitis C, HIV or Measles, and have been shown to produce strong antibody responses in mice. Detailed information on the cellular and antibody responses to these VLP vaccines will be aligned with GLP processes to support future clinical trials in man, providing support for the development of urgently needed vaccines against a range of infectious diseases.