CORE--INTERVENTION

干预核心的总体目标是推进护理干预科学，以预防或管理弱势群体的慢性疾病。随着慢性病的流行，开发和测试护理干预措施以预防和管理慢性病变得越来越重要。有大量的描述性文献描述了患有慢性疾病的生活是什么样的，然而，大量的工作在那个阶段萎靡不振，从未发展到干预措施。干预核心的具体目标是：1)促进研究者从描述性研究转向干预措施的开发和测试；2)通过检查选定结果的中介来探索干预措施的作用机制；3)通过探索治疗效果的调节因子来帮助研究者评估被测试干预措施的不同有效性，特别强调脆弱性指标作为潜在调节因子的作用。4)通过确定最适用的环境和问题，探索量身定制的干预措施的使用；5)提高成本分析技术的知识，并在干预研究中增加成本效益和成本效益分析的使用。干预核心将采用以下策略来实现其目标：就问题识别和干预措施设计进行磋商；就分析干预效果的中介和调节因素的统计技术进行协商；成本分析咨询；研讨会和座谈会；以及为该地区其他机构的研究人员设计干预措施的继续教育项目。

The Intervention Core's overall goal is to advance the science on nursing interventions to prevent or manage chronic illness in vulnerable populations. With the prevalence of chronic illness, it becomes increasingly important to develop and test nursing interventions to prevent and manage chronic illness. There is a substantial body of descriptive literature 'Dn what it is like to live with a chronic illness, however, a great deal of the work languishes at that stage and never moves to the development of interventions. The Specific Aims of the Intervention Core are to 1) facilitate movement of investigators from descriptive research to the development and testing of interventions, 2) explore the mechanisms of action of interventions by examining the mediators of selected outcomes, 3) help investigators evaluate the differential effectiveness of tested interventions by exploring moderators of treatment effect, with particular emphasis on the role of indicators of vulnerabilities as potential moderators, 4) explore the use of tailored interventions by identifying the contexts and problems for which they are most applicable, and 5) advance knowledge of cost analysis techniques and increase the use of cost benefit and cost effectiveness analyses in intervention studies. The Intervention Core will employ the following strategies to achieve its aims: consultation on problem identification and intervention design; consultation on statistical techniques for the analysis of mediators and moderators of intervention effects; consultation on cost analysis; seminars and colloquia; and continuing education programs on designing interventions for researchers in other institutions throughout the region.