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GENETICS OF GRAFT VERSUS HOST DISEASE

GENETICS OF GRAFT VERSUS HOST DISEASE
移植物抗宿主疾病的遗传学
批准号:
6297189
负责人:
David Ginsburg
金额:
$0.02万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30

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项目成果

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中文摘要
翻译
该项目的总体目标是确定HLA以外的导致移植物抗宿主病(GVHD)的基因。 GCRC的遗传学核心设施将用于从研究对象中生产经鉴定的永生化细胞系。 淋巴细胞将用EBV永生化,以提供可再生的细胞和DNA供分析。 这些淋巴母细胞的可用性将有助于描绘特定基因。
英文摘要
The overall aim of this project is to identify the gene(s) other than HLA that contribute to Graft-versus-host disease (GVHD). The Genetics Core Facility of the GCRC would be utilized for the production of immortalized cell lines from research subjects, as they are identified. Lymphocytes will be immortalized with EBV for the purpose of providing a renewable supply of cells and DNA for analysis. The availability of these lymphoblast cells will facilitate delineation of the specific gene(s).
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The Molecular Genetics of Hemostasis
The Molecular Genetics of Hemostasis
Identifying novel genetic risk factors for venous thromboembolism (VTE)
Identifying novel genetic risk factors for venous thromboembolism (VTE)
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