IN VITRO ASSESSMENT OF LIPID PEROXIDATION IN CARDIAC PATIENTS
IN VITRO ASSESSMENT OF LIPID PEROXIDATION IN CARDIAC PATIENTS
批准号:
6265176
负责人:
SOTIRIOS TSIMIKAS
金额:
$1.15万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30
关键词:
angina pectoris antibody specificity biomarker blood chemistry blood vessel prosthesis clinical research coronary artery diagnosis design /evaluation heart disorder diagnosis heart revascularization heart transplantation human subject lipids myocardial infarction oxidation reduction reaction peroxidation postoperative state preoperative state transplant rejection
中文摘要
评估各种心脏疾病(如稳定型心绞痛、不稳定型心绞痛、心肌梗死、血管成形术前/后和/或冠状动脉支架置入术或心脏移植/排斥反应)中血液中脂质过氧化的存在。 将使用氧化特异性抗体的测定来评估心脏病患者血液中是否存在抗体作为长期脂质过氧化的标志物。
英文摘要
Assess the presence of lipid peroxidation in the blood in various cardiac disorders such as stable angina, unstable angina, myocardial infarction, pre/post angioplasty and/or coronary stent placement, or cardiac transplantation/rejection. Assays for presence of oxidation-specific antibodies will be utilized to assess the presence or absence of antibodies in the blood of cardiac patients as a marker of long-standing lipid peroxidation.
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会议论文
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依托单位:
海外基金