CHARACT OF CRYSTALS OF ION CHANNEL, KCSA, & OF MEMBRANE FUSION PROTEIN, P97

我们感兴趣的是具有生物学重要性的蛋白质 功能，通过动态过程实现其活动 这是结构变化的结果。 这两种蛋白质 本研究中涉及的KcsA和P97，是很好的例子。 这样的分子。 KcsA是链霉菌的钾离子通道 利维丹人，理解这一点将对一个 许多生物过程，如神经冲动。 P97是一个 参与双层融合的蛋白质，其结构也 进一步了解生物学的一些重要领域， 其中的一个例子是Ca 2+调节的融合（胞吐） 突触囊泡释放神经递质。

We are interested in proteins with biologically important functions, that achieve their activities through dynamic processes which result from structural changes. The two proteins that we are concerned with in this study, KcsA and P97, are excellent examples of such molecules. KcsA is a potassium ion channel from Streptomyces lividans, the understanding of which would have repercussions for a number of biological processes, such as nerve impulses. P97 is a protein involved in bilayer fusion, the structure of which would also further the understanding in a number of important areas of biology, an example of which would be the Ca2+-regulated fusion (exocytosis) of synaptic vesicles in the release of neurotransmitters.