BACULOVIRUS DNA REPLICATION FACTORS & BACULOVIRUS ORIGINS FOR DNA REPLICATION

从一项对当前文学的调查中可以清楚地看到， 远端关节内骨折复位不良与骨折的关系 桡骨和随后发生的放射腕骨关节病 临床上很重要，但知之甚少。同样明显的是， 腕关节的非线性接触有限元分析 非常适合于详细调查的可行的计算方案 在放射腕关节的局部组织应力。将这些组合在一起 点，有限元分析提供了一个有用的工具 研究不精确还原的力学含义 桡骨远端关节内骨折。的广泛目标 提出的研究是一种经过充分验证的开发 放射腕关节的计算模型，与 以前开发的实验模型，将能够提供 指导如何严格地改善桡骨远端的功能 关节内骨折处理技术。这件事的重点是 功是初始关节内的力学关系 桡骨远端骨折，随之而来的不精确复位 关节不协调，最后出现骨关节病。这 三维有限元模型将包括半径、两个 腕骨(月骨和舟状骨)和关节 在这些骨头之间。模型几何图形将从 冷冻显微镜切片照片，以前从 身体手腕。

It is clear from a survey of current literature that the relationship between malreduced intra-articular fracture of the distal radius and the subsequent onset of radiocarpal osteoarthrosis is clinically important, yet poorly understood. It is also clear that nonlinear contact finite element analysis of the radiocarpal joint is a feasible computational option well-suited for detailed investigation of local tissue stresses in the radiocarpal joint. Combining these points, finite element analysis provides a useful tool for investigating the mechanical implications of imprecise reduction of intra-articular fracture of the distal radius. The broad objective of the proposed research is the development of a well-verified computational model of the radiocarpal joint, which, in concert with previously developed experimental models, will be capable of providing guidance toward rigorously grounded improvements in distal radius intra-articular fracture management techniques. The focus of this work is the mechanical relationship between initial intra-articular fracture of the distal radius, subsequent imprecise reduction of articular incongruency, and final onset of osteoarthrosis. This three-dimensional finite element model will include the radius, two carpal bones(the lunate and the scaphoid), and the articulations between these bones. The model geometry will be obtained from photographs of cryomicrotome sections previously obtained from a cadaver wrist.