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ICF: Unmanned aerial vehicles ('drones') for sustainable vaccine research and improving equity in vaccine delivery: a feasibility study in The Gambia

ICF: Unmanned aerial vehicles ('drones') for sustainable vaccine research and improving equity in vaccine delivery: a feasibility study in The Gambia
ICF:用于可持续疫苗研究和提高疫苗交付公平性的无人机(“无人机”):冈比亚的可行性研究
批准号:
MR/X011771/1
负责人:
Ed Clarke
金额:
$12.84万
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2022
资助国家:
英国
项目状态:
未结题
起止时间:
2022 至 --

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中文摘要
翻译
在撒哈拉以南非洲的低收入国家,进行具有国际竞争力的卫生研究,并向所有人提供高质量的医疗保健,需要无数次的机动车旅行。其中许多旅程距离很短(30公里),运输的是小而轻的有效载荷,包括疫苗、药品、输血和研究样本(例如,临床试验中成人和儿童的血液样本)。然而,由于道路状况恶劣,以及对灵活、坚固、寿命长的车辆的需求,目前大多数旅行都是使用柴油或汽油动力的四轮驱动。像这样的车辆是效率最低、对环境和健康危害最大的交通工具之一。在非洲,车辆排放的温室气体每年增加7%。气候变化已经对非洲的粮食安全产生了影响,并改变了疟疾和黄热病等由蚊子叮咬引起的疾病的传播。因此,发挥减少这些排放的带头作用非常重要。车辆,特别是老式车辆,也会产生空气污染物,增加患心肺疾病、糖尿病和中风的风险。这些疾病在非洲已经在迅速增加,因此需要新的方法来扭转这一趋势。环境噪音(或噪音污染)主要来自撒哈拉以南非洲城市环境中的交通,可能导致睡眠和情绪紊乱、注意力难以集中和心脏病。减缓这些疾病的增长也很重要。最后,世界大部分地区的道路交通死亡人数正在下降,但在非洲许多地区却在增加。目前,它们是西非15至29岁人群中最常见的死亡原因,其中近一半是行人。通过研究其他运输方式来减少车辆数量也是解决这一重要负担的一种方法。这项研究将确定在西非冈比亚使用无人机(或无人机)取代公路车辆运输研究样本和医疗用品的可行性、成本和环境影响。无人机将采用太阳能改装,因此在功率方面是碳中性的。我们将专门测试无人机,首先将疫苗研究参与者的血液样本运送到中心实验室进行处理,其次将乙肝疫苗运送到农村卫生站,允许新生儿在出生第一天接种疫苗。这些因素包括飞行时间(时间和距离)、在稳定温度下保持血液样本和疫苗的能力、电力消耗、成本和安全,以及季节性因素对飞行的影响,如来自撒哈拉的风暴和哈马坦风。这些技术数据将得到采访和小组讨论的补充,旨在更广泛地了解无人机飞行在冈比亚和其他类似环境中可能会被视为如何。这项研究将与冈比亚卫生部和Arda合作进行,Arda是一家旨在为非洲描述的目的开发无人机技术的公司。通过这些伙伴关系,预计这项研究对环境可持续研究和医疗保健的未来影响将最大化。
英文摘要
In low-income countries in sub-Saharan Africa, conducting internationally competitive health research, and providing high quality healthcare to all, requires numerous motor vehicle journeys. Many of these journeys are of short distance (<30 km) and are undertaken to transport small, light-weight payloads including vaccines, medicines, blood transfusions and research samples (e.g., blood samples from adults and children in clinical trials). However, due to poor road conditions and the need for flexible, robust, long-lived vehicles, most journeys are currently undertaken in diesel- or petrol-powered four-wheel-drives. Vehicles like this are some of the least efficient and most environmentally- and health-damaging modes of transport operating.Emissions of greenhouse gases from vehicles in Africa are increasing by 7% each year. Climate change is already impacting on food security in Africa as well as changing the spread of diseases like malaria and yellow fever that result from mosquito bites. Leadership to reduce these emissions is therefore important. Vehicles, particularly older vehicles, also produce air pollutants which increase the risk of heart and lung disease, diabetes, and strokes. These are diseases that are already increasing rapidly in Africa so new ways to reverse this trend are needed. Environmental noise (or noise pollution) comes mainly from traffic in urban settings in sub-Saharan Africa and can cause sleep and mood disturbances, difficulties concentrating and heart disease. Slowing down increases in these diseases is important too. Finally, road traffic deaths are going down across much of the world, but are increasing in many parts of Africa. They are currently the most common cause of death in 15 to 29-year-olds in West Africa, with nearly half of these deaths being pedestrians. Reducing vehicle numbers through looking at other modes of transport is also one way which may address this important burden.This study will establish the feasibility, costs, and environmental impacts of using unmanned aerial vehicles (or 'drones') to replace road vehicles for the transport of research samples and healthcare supplies in The Gambia, West Africa. The drones will be solar changed and thus carbon neutral with respect to power.We will specifically test drones first, to transport blood samples from participants in vaccine studies to a central laboratory for processing, and second, to transport hepatitis B vaccines to rural health posts allowing newborn babies to receive the vaccines on the first day of life as recommended.Factors including the length of flights (time and distance), the ability to maintain blood samples and vaccines at stable temperatures, power consumption, costs, and safety as well as the impacts of seasonal factors, such as storms and the harmattan winds from the Saharan, on flights will all be explored. This technical data will be complemented by interviews and group discussions aiming to gain a broader understanding of how drone flights are likely to be perceived in The Gambia and other comparable settings. The study will be conducted in partnership with the Gambian Ministry of Health and Arda, a company aiming to develop drone technology for the purposes described in Africa. Through these partnerships the future impact of the study on environmentally sustainable research and healthcare are expected to be maximized.
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会议论文
HPV, STI and AMR in West Africa: estimating population burden and understanding exposures to accelerate vaccine impact and drive new interventions
A non-inferiority trial to assess the safety and immunogenicity of yellow fever vaccine dose sparing strategies for campaign and programmatic use
  • 批准号:
    MC_EX_MR/R006148/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $140.08万
  • 财政年份:
    2017
  • 负责人:
    Ed Clarke
  • 依托单位:
A randomised, observer-blind, non-inferiority trial to evaluate alternative human papillomavirus vaccination schedules in young females in West Africa
  • 批准号:
    MC_EX_MR/N006070/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $211.01万
  • 财政年份:
    2015
  • 负责人:
    Ed Clarke
  • 依托单位:
A randomised controlled trial to evaluate the effect of maternal or neonatal pneumococcal conjugate vaccination on pneumococcal carriage in early life
  • 批准号:
    MC_EX_MR/M007529/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $180.51万
  • 财政年份:
    2014
  • 负责人:
    Ed Clarke
  • 依托单位:
海外基金