FOUNDATION COLONY FOR MOUSE REPOSITORY

承包商将被要求保持老鼠繁殖/屏障 为校内调查人员提供近亲和同源基因的设施 NIAID不能轻易用于研究的小鼠品系 在免疫学和传染病方面。的最新发展 转基因技术，包括基因打靶，开辟了一种新的和 细胞生物学中激动人心的时代。这些工具使科学家能够 探索单个基因产物作用的重要性和作用机制 在活体内，并建立人类疾病的动物模型。

The Contractor will be required to maintain a mouse breeding/barrier facility to provide intramural investigators with inbred and congenic strains of mice not readily available from the NIAID for use in research in immunology and infectious diseases. The recent development of transgenic techniques, including gene targeting has opened up a new and exciting era in cell biology. These tools are allowing scientists to explore the importance and mechanism of action of individual gene products in vivo and to create animal models for human diseases.