Differences in neonatal immune regulation in the developing and developed world: implications for neonatal vaccinations?

该项目将通过比较巴布亚新几内亚和西澳大利亚新生儿之间的免疫反应，研究不利的生活条件，如微生物大量接触、营养不良、环境烟草烟雾和疟疾感染对新生儿免疫系统发育的影响。这项研究将帮助我们了解发展中国家儿童对传染病的高度易感性，并制定更好的预防策略。

This project will study the effect of adverse living conditions such as high microbial exposure, malnutrition, environmental tobacco smoke and malaria infection on the development of a newborn's immune system,by comparing immune response between newborns in Papua New Guinea and in Western Australia. This study will help us to understand the high susceptibility of children in the developing world for infectious diseases and to develop better prevention strategies.