CORE--BIOSTATISTICS

生物统计核心将提供统计、数据管理和数据 为CFAR调查人员提供入门支持。特别是，生物统计学 核心将在大量的 华盛顿大学和弗雷德大学的生物统计学教授 哈钦森癌症研究所正在开发新的统计学 艾滋病研究方法和CFAR生物医学研究人员。此链接 将使两个群体都受益。生物统计核心将提供先进的 统计方法和专门知识是在Dr。 弗莱明的艾滋病方法论奖，授予CFAR调查人员；临床和 利用生物统计学核心的实验室研究人员将提供 用于分析的数据集，这些数据集可能会推动新的 方法论资助下的统计方法。促进和便利 这些多学科的互动将成为生物统计学的核心1) 提供关于研究设计、表格、 设计评估和预试，以及数据分析；提供数据录入 和数据管理服务；开发、调整和/或实施新的或新颖的 根据需要使用统计方法；维护符合以下条件的计算设施 向任何CFAR调查员提供(现场和远程登录)；2) 在标准化临床、行为和 威斯康星大学和妇幼保健中心艾滋病研究的统计方法；3)增加 参与行为的个人之间的协作关系 研究和生物统计界；以及4)为 参与行为研究和生物统计学的个人 社区；以及4)为参与健康的个人提供支持 通过协作链接提供服务和国际艾滋病/艾滋病毒研究 与医疗服务和国际核心部门合作。利用CFAR资金 作为种子，我们设想开发一个数据管理和统计 分析中心，部分运营资金来自收费- 服务数据录入和数据管理。这将允许个人CFAR 调查人员整合这些领域的资源，并将确保统一， 高质量的数据库。生物统计学核心还将形成一个 对于没有独立调查人员的新调查人员来说，这是特别宝贵的资源 资金和需要高级人才的老牌调查人员 生物统计学专业知识，以进行创新或意外的研究 方向。

The Biostatistics Core will provide statistical, data management and data entry support for CFAR investigators. In particular, the biostatistical core will provide a crucial link between the large number of biostatistical faculty at the University of Washington and the Fred Hutchinson Cancer Research Institute who are developing new statistical methods for AIDS research and the CFAR biomedical researchers. This link will benefit both groups. The Biostatistical Core will provide advanced statistical methods and expertise, which have been developed under Dr. Flemming's AIDS Methodology grant, to CFAR investigators; the clinical and laboratory researchers utilizing the Biostatistical Core will provide datasets for analysis which may motivate the development of new statistical methods under the Methodology grant. To promote and facilitate these multi-disciplinary interactions the Biostatistics Core will 1) provide statistical collaboration and consultation on study design, forms, design evaluation and pretesting, and data analysis; provide data entry and data management services; develop, adapt and/or implement new or novel statistical methods as needed; maintain computing facilities which are available (both on site and by remote login) to any CFAR investigator; 2) provide leadership in efforts to standardize clinical, behavioral and statistical methodology in AIDS research at the UW and FHCRC; 3) increase collaborative relationships between individuals involved in behavioral research and the biostatistical community; and 4) provide support for individuals involved in behavioral research and the biostatistical community; and 4) provide support for individuals involved in health services and international AIDS/HIV research through collaborative links with the health Services and International cores. Using the CFAR funding as the seed, we envision developing a data management and statistical analysis center with a portion of operating funds coming from fee-for- service data entry and data management. This will allow individual CFAR investigators to combine resources in these areas and will ensure uniform, high quality databases. The Biostatistical Core will also form a particularly valuable resource for new investigators without independent funding and for established investigators in need of advanced biostatistical expertise to pursue innovated or unanticipated research directions.