EFFECTS OF LACTOBACILLUS CASEI GG IN CHILDREN W/ SHORT BOWEL SYNDROME
EFFECTS OF LACTOBACILLUS CASEI GG IN CHILDREN W/ SHORT BOWEL SYNDROME
批准号:
6264291
负责人:
JUDITH M SONDHEIMER
金额:
$1.99万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30
关键词:
Lactobacillus casei bacteria infection mechanism child (0-11) clinical research disease /disorder proneness /risk gastrointestinal nutrient absorption hepatotoxin host organism interaction human subject human therapy evaluation lipid metabolism nutrition related tag short bowel syndrome small intestines
中文摘要
我们建议测试两个有关儿童短肠综合征的相关假设。 首先,我们建议测试一个广泛接受的假设,即短肠综合征的儿童在剩余的小肠中细菌过度生长的发生率很高。 其次,我们建议检验以下假设:改变此类患者肠道内的常驻植物群将导致粪便中脂肪减少、粪便植物群改变以及影响大多数此类患者的肝毒性证据改善。
英文摘要
We propose to test two linked hypotheses regarding children with short bowel syndrome. First, we propose to test the widely held assumption that children with short bowel syndrome have a high incidence of bacterial overgrowth in the remaining small bowel. Secondly, we propose to test the hypotheses that changing the resident flora in the intestine of such patients will result in a decrease in fat loss in the stool, a change in stool flora and an improvement in the evidence of hepatic toxicity that affects most of these patients.
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EFFECTS OF LACTOBACILLUS CASEI GG IN CHILDREN W/ SHORT BOWEL SYNDROME
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批准号:6305019
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项目类别:
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资助金额:$1.99万
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财政年份:--
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负责人:JUDITH M SONDHEIMER
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依托单位: