COMPARE LOW DOSE TO TRADITIONAL ACTH TESTS DURING GLUCOCORTICOID WITHDRAWAL

该方案比较了两种肾上腺反应性测试（ 传统的高剂量ACTH试验与新的低剂量ACTH试验） 最近接受过外源性糖皮质激素的患者 在这些 患者，将每月进行一次高剂量试验，直至 就正常了 此后，将进行低剂量试验，直至 正常化 将考虑第二次事件发生前的时间间隔 随着下丘脑-垂体-肾上腺轴的完全恢复， 并应确认这种新工具的更高灵敏度， 患者必须小心肾上腺皮质激素的可能性 停用类固醇后功能不全。

This protocol compares two tests of adrenal responsiveness (the traditional high dose ACTH test vs the new low dose ACTH test) in patients who have received exogenous glucocorticoids in the recent past. In these patients, the high dose test will be performed on a monthly basis, until it normalizes. After that, the low dose test will be performed until it normalizes. The time interval until this second event will be considered as the complete recovery of the hypothalamic - pituitary - adrenal axis, and should confirm the higher sensitivity of this new tool for assessing how long patents have to be careful about the possibility of adrenal insufficiency after steroid withdrawl.