RANDOMIZED EVALUATION OF MECHANICAL ASSISTANCE FOR CONGESTIVE HEART FAILURE

这是一项多中心、随机临床试验，旨在评价左心室辅助装置治疗心力衰竭的有效性、安全性和成本效益。 明尼苏达大学的10名患有终末期充血性心力衰竭的患者将随机接受标准药物治疗（n=5）或机械左心室辅助装置（n=5），并随访两年。 主要终点是患者生存率。 次要终点是生活质量、住院和费用。 分配接受机械左心室辅助装置治疗的患者将在GCRC中康复。 两组患者将作为GCRC门诊患者每月随访一次。

This is a multicenter, randomized clinical trial to evaluate the efficacy, safety and cost-effectiveness of a left ventricular assist device in the treatment of heart failure. Ten patients at the University of Minnesota with end-stage congestive heart failure will be randomized to either standard medical therapy (n=5) or a mechanical left ventricular assist device (n=5) and followed for two years. The primary end point is patient survival. Secondary end points are quality of life, hospitalization, and cost. Patients assigned to treatment with the mechanical left ventricular assist device will convalesce in the GCRC. Patients in both groups will be followed at monthly intervals as GCRC outpatients.