CENTER ON TOBACCO USE SUSCEPTIBILITY AND INTERVENTION

拟议的TTURC反映了几个独特的优势。首先，该中心汇集了五位在烟草研究领域具有不同专业知识的杰出项目负责人（Leslie博士，Janner博士，PotInn博士，Pechman博士和Tengs博士）。 这些学者中的每一位都在药理学、神经科学、人类发展、社会和健康心理学、社区健康促进和卫生政策分析等各自学科中取得了杰出成就。 这些科学家将合作确定动物尼古丁依赖和人类烟草易感性和使用的关键预测因素。该合作的一个主要目标是建立一个烟草易感性和使用的共享概念模型，可用于整合多层次分析的实验结果（即，生物、行为、发展、人际关系和流行病学/社区水平），并将这些发现转化为干预策略（即，药理学、行为学、社会营销和卫生政策策略），将评估其公共卫生功效和成本效益。TTURC的第二个主要优势是它包含了四个高度互动的核心，每个核心都是为了促进烟草易感性，使用和干预领域的成功跨学科合作而设计的。 跨学科核心将实施结构化活动，以促进科学合作（例如，团队研讨会，务虚会），并进行系统的自我研究的合作TIURC的成员之间在五年的时间内，基于前因，中间过程和跨学科研究的科学成果的分类模型。 信息学核心（由Shankle博士领导）将开发几个有价值的信息资源，包括一个共享的关系数据库，以促进跨多个TTURC项目的数据集和研究结果的整合，以及一个交互式TTURC网站），所有这些都旨在促进更有效的跨学科合作Whitely和Fallon）整合了研究项目和跨学科和信息学核心中强调的理论和方法论观点。它将提供一系列广泛的跨学科培训机会，直接响应青年烟草预防行动工作组报告（1998年）中概述的培训优先事项。最后，行政核心将由Leslie和Stokols博士共同指导，他们都拥有丰富的大学行政经验，并活跃于药理学，神经科学，社区健康促进，社会生态学和跨学科理论发展领域。国家方案执行干事将监督技术、商业和资源利用中心的互动活动，目的是促进项目小组成员、研究受训人员和工作人员以及外部和内部咨询委员会成员之间有效的跨学科合作。

The proposed TTURC reflects several unique strengths. First, the Center brings together five eminent project leaders with diverse expertise in the field of tobacco research (Drs. Leslie, Janner, PotInn, Pechman, and Tengs). Each of these scholars has achieved distinction in their respective disciplines of pharmacology, neuroscience, human development, social and health psychology, community health promotion, and health policy analysis. These scientists will work collaboratively to identify key predictor of nicotine dependency in animals and tobacco susceptibility and use in humans. A major goal of the collaboration is to establish a shared conceptual model of tobacco susceptibility and use that can be used to integrate experimental findings across multiple levels of analysis (i.e., biological, behavioral, developmental, interpersonal, and epidemiological/community levels), and to translate these findings into intervention strategics (i.e., pharmacological, behavioral, social marketing, and health policy strategies) that will be evaluated for their public health efficacy and cost effectiveness. A second major strength of the TTURC is its incorporation of four highly interactive cores, each strategically designed to promote successful transdisciplinary collaboration in the field of tobacco susceptibility, use, and intervention. The Transdisciplinary Core will implement structured activities to foster scientific collaboration (e.g., team workshops, retreats), and also conduct a systematic self study of collaboration among members of the TIURC over a five-year period, based on a taxonomic model of the antecedents, intermediate processes, and scientific outcomes of transdisciplinary research. The Informatics Core (led by Dr. Shankle) will develop several valuable informational resources, including a shared relational data base to facilitate the integration of data sets and research findings across multiple TTURC projects and an interactive TTURC web site), all designed to promote more effective transdisciplinary collaboration The Career Development Core (co-directed by Drs. Whitely and Fallon) integrates the theoretical and methodological perspectives emphasized in the research projects and the Transdisciplinary, and Informatics Cores. It will afford a wide array of transdisciplinary training opportunities that are directly responsive to the training priorities outlined in the Report of the Working Groups of the Youth Tobacco Prevention Initiative (1998). Finally, the Administrative Core will be co-directed by Drs. Leslie and Stokols, both of whom have extensive university administrative experience and are active in the fields of pharmacology, neuro5cience, community health promotion, social ecology, and transdisciplinary theory development. The CO-PIs will oversee interactive activities of the TTURC with the goal of promoting effective transdisciplinary collaboration among the project team members research trainees and staff and members of the External and Internal Advisory Boards.