CORE--SUBJECT RECRUITMENT, PROCUREMENT, RETENTION AND FOLLOWUP

受试者招募、样本采集、保留和随访 核心旨在为所有参与者提供中央接入点， 患者采样的协调。 本核心的目的是 确保足够的样本收集，同时尽量减少混淆 当多个项目访问相同的患者时，这是可能的。 这次中央 获取点将使调查人员能够利用信息 通过集中样本知识， 空房的 该核心还将最大限度地减少答复者的负担，因为 多余的问卷或信息将被删除，重复 取消了抽样，并可能减少了必要的抽样， 创造性地分享样品。 基本上，这个核心负责收集唾液， 项目1和2的菌斑样本，交付时的脐带血， 唾液和母乳用于项目3，血液样本用于项目4。 项目4. 核心会收集这些样本并分发给 每个核心都有调查人员，同时在核心中保留储备。 核心 还负责收集人口统计、医疗、 研究对象的产科、牙科和营养数据。

The Subject Recruitment, Sample procurement, Retention, and Follow-up Core is designed to provide central access point to all participants for the coordination of patient sampling. The purpose of this Core is to insure adequate sample collection, while minimizing the confusion possible when multiple projects access the same patients. This central acquisition point will enable investigators to build on the information collected by the entire center by having centralized knowledge of sample availability. This Core will also minimize respondent burden because redundant questionnaires or information will be eliminated, repeated sampling eliminated, and possibly reduced the sampling necessary through creative sharing of samples. Basically, this Core is responsible for the collection of saliva and plaque samples for projects 1 & 2, cord blood at the time of delivery for project 3, saliva and breast milk for project 3, and blood samples for project 4. The Core will gather these samples and distribute to investigators in each core while keeping reserves in the core. The Core is also responsible for the collection of demographic, medical, obstetrical, dental, and nutritional data from study subjects.