COMPARATIVE AND DEVELOPMENTAL BIOLOGY OF THE HUMAN PARANASAL SINUSES

副鼻窦或空气空间是现代鼻咽癌的一个显著特征 人类的脸。事实上，它们的存在可能是一个古生物学标志 我们自己的物种，智人。副鼻窦的功能 在很大程度上仍不为人所知，关于它们的作用的理论与 面部结构的非功能性副产品与结构的副产品 与鼻腔一样，在取暖和 吸气空气的湿化。这项研究将调查 两人副鼻窦与鼻腔的关系 以及一系列非人类灵长类和其他哺乳动物。 研究将包括三个主要部分：1)比较 在实验室使用尸检材料对该区域进行解剖 西奈山医学院的杰弗里·莱特曼博士，包括 人类陆生和水生动物的发育和组织学分析 哺乳动物.2)外部骨性标志和测量的颅骨测量学研究 美国自然历史博物馆的内部卷，使用这两种 卡尺和三维数字化仪；3)成像的使用 计算机辅助断层扫描(CT扫描)和磁力成像等技术 磁共振成像(MRI)-扫描)，这将提供机会 以一种以前无与伦比的方式来可视化这个地区。 三维重建将允许计算体积 以及副鼻窦和鼻腔的粘膜面积以及 更详细地研究发育系列。这项研究将形成 塞缪尔·马奎斯先生博士论文的核心 纽约州立大学人类学博士生，其共同论文 顾问是Eric Delson教授(雷曼兄弟和美国博物馆 自然历史)和杰弗里·莱特曼(西奈山)。 这个项目是他们之前资助的面部研究的结果。 旧世界猴子和猿类的建筑，以及关于发展和 人类和类人猿上呼吸道的进化。 马奎兹先生将在他们的机构接受培训和指导， 他的研究将通过三方互动进行指导。在……里面 此外，另一名纽约州立大学的研究生和一名雷曼兄弟的高层 将为本科生提供类似的培训和机会 协助马奎兹先生开展他的研究项目。两者都有 德尔森和莱特曼负责培训了许多 在解剖学和医学领域取得丰硕成就的研究生 生物医学研究的人类学方面。

Paranasal sinuses, or air spaces, are a prominent feature of the modern human face. In fact, their presence may be a paleontological marker for our own species, Homo sapiens. The function of the paranasal sinuses remains largely unknown, and theories as to their role vary from that of non-functional byproducts of facial structure to that of structures playing a key role, along with the nasal cavity, in heating and humidification of inspired air. This research will investigate the relationship between the paranasal sinuses and nasal cavity in both humans and a range of non-human primates and other mammals. The research will involve three main components: 1) comparative dissections of the region using postmortem materials in the laboratory of Dr. Jeffrey Laitman at the Mount Sinai School of Medicine, including developmental and histological analyses of humans terrestrial and aquatic mammals; 2) craniometric study of external bony landmarks and measurement of internal volumes at the American Museum of Natural History, using both calipers and a three dimensional digitizer; 3) the use of imaging technologies such as computer assisted tomographs (CT-scans) and magnetic resonance imaging (MRI)-scans) which will provide the opportunity to visualize this region in a manner which was unapproachable previously. Three dimensional reconstructions will permit the calculation of volume and mucosal area of paranasal sinuses and nasal cavities as well as to examine developmental series in greater detail. This research will form the core of the doctoral dissertation of Mr. Samuel Marquez, graduate student in the Ph.D. Program in Anthropology of CUNY, whose co-thesis advisors are Professors Eric Delson (Lehman and the American Museum of Natural History) and Jeffrey Laitman (Mount Sinai). The project is an outgrowth of their previous funded research on facial architecture in Old World monkeys and apes, and on development and evolution of the upper respiratory tract in humans and apes, respectively. Mr. Marquez will be trained and mentored by them at their institutions, and his research will be directed through a three-way interaction. In addition, another CUNY graduate student and an upper-level Lehman undergraduate will be provided similar training as well as the opportunity to assist Mr. Marquez in the carrying out of his research project. Both Delson and Laitman have been responsible for the training of numerous graduate students who have gone on to productive careers in anatomical and anthropological aspects of biomedical research.