CORE--BIOSTATISTICS

生物统计核心将提供统计和数据输入支持 对CFAR调查人员来说。特别是，生物统计学核心将 在大量的生物静态教员之间提供了一个至关重要的纽带 在华盛顿大学和弗雷德·哈钦森癌症研究中心 正在为艾滋病研究开发新的统计方法的研究所 以及使用CFAR的临床和实验室研究人员。此链接 将使两个群体都受益。生物统计核心将提供先进的 统计方法和专门知识是在Dr。 弗莱明的艾滋病方法论奖，授予CFAR调查人员；临床和 利用生物统计学核心的实验室研究人员将提供 用于分析的数据集，这些数据集可能会推动新的 方法论资助下的统计方法。推广和推广 促进这些多学科的互动--生物统计学核心 1)提供研究方面的统计协作和咨询 设计；表格设计、评估和预试；以及数据分析；2) 按计费系统提供数据录入服务；3) 合作撰写手稿，特别注意 准确描述研究设计、数据分析和解释 结果；4)在CFAR的数据和安全监测委员会任职 根据需要，调查人员；5)开发、改编和/或实施新的或新颖的 根据需要采用统计方法；以及6)维护计算设施(3 S)(现场和远程均可使用 登录)到任何CFAR调查员。生物静态核心将形成一个 对于制定建议的新调查人员来说，这是特别宝贵的资源 对于同行审查的资金和已建立的竞争 需要高级生物统计学专业知识的调查人员 创新或意想不到的研究方向。

The Biostatistics Core will provide statistical and data entry support for CFAR investigators. In particular, the biostatistical core will provide a crucial link between the large number of biostatical faculty at the University of Washington and the Fred Hutchinson Cancer Research Institute who are developing new statistical methods for AIDS research and the clinical and laboratory researchers using the CFAR. This link will benefit both groups. The Biostatistical Core will provide advanced statistical methods and expertise, which have been developed under Dr. Fleming's AIDS Methodology grant, to CFAR investigators; the clinical and laboratory researcher utilizing the Biostatistical Core will provide datasets for analysis which may motivate the development of new statistical methods under the Methodology grant. To promote and facilitate these multidisciplinary interactions the Biostatistics Core will 1) provide statistical collaboration and consultation on study design; forms design, evaluation and pretesting; and data analysis; 2) provide data entry services according to a charge-back system; 3) collaborate in the writing of manuscripts, paying special attention to accurate descriptions of study design, data analysis and interpretation of results; 4) serve on Data and Safety Monitoring Boards for CFAR investigators, as needed; 5) develop, adapt and/or implement new or novel statistical methods as needed; and 6) maintain computing facilities (3 DECstations 3100's) which are available (both on site and by remote login) to any CFAR investigator. The Biostatical Core will form a particularly valuable resource for new investigators developing proposals for peer-reviewed competition for funding and for established investigators in need of advanced biostatistical expertise to pursue innovative or unanticipated research directions.