HIV-PREVENTION AND VACCINE PREPAREDNESS IN NIGERIA

摘要：美国马里兰大学巴尔的摩分校（UM）人类病毒学研究所（IHV）、医学院和牙科学院以及研究生项目提议对现有的Fogarty AIRTP进行补充，以包括尼日利亚预防艾滋病毒和艾滋病的多学科培训和研究。在人类病毒学研究所的科学家与乔斯大学合作者之间建立良好的科学关系的基础上，这一地理扩展将支持在尼日利亚高原州乔斯开展艾滋病毒预防和艾滋病毒临床试验方面的研究和培训。该计划的目的是：1)在艾滋病毒预防和疫苗准备相关领域为医生、流行病学家或实验室医学专业人员提供长期（博士后）培训，包括艾滋病毒监测和预防、血库、艾滋病毒快速诊断、临床（包括围产期）和疫苗试验设计和实施、此类研究的实验室支持、行为干预、数据管理和分析。2)对尼日利亚主要调查人员和支助人员进行艾滋病毒方面的短期最先进的密集培训，以加强当地在艾滋病毒预防和疫苗准备方面开展相关合作研究活动的能力。兹建议后一种培训活动将是本增编的主要重点，并将包括国内讲习班，以便接触到更多的受训人员，并为应用和扩大受训人员所接受的培训提供一个论坛。3)开始加强乔斯中心的进程，为来自该国不同地区和其他非洲国家的候选人提供培训。为了实现这些目标，将拟订和完善一项培训活动方案，以满足非洲人口最多的国家目前的需要，这个国家的非B级艾滋病毒-1的传播迅速增加，并且在处理艾滋病毒/艾滋病流行病方面新的开放态度。这项应用的一个关键组成部分是“南南”合作，通过在乌干达艾滋病支持组织（TASO）和未来的乔斯中心进行短期培训。

Abstract: The Institute of Human Virology (IHV) and the Schools of Medicine & Dentistry and the Graduate Program of the University of Maryland, Baltimore (UM) propose to supplement an existing Fogarty AIRTP to include multi-disciplinary training and research in the prevention of HIV and AIDS in Nigeria. Building upon well-established scientific relationships between scientists from the Institute of Human Virology and collaborators at the University of Jos, this geographic expansion will support research and training in HIV prevention and implementation of HIV clinical trials in Jos, Plateau State, Nigeria. The aims of the program are: 1) To provide long term (postdoctoral) training to physicians, epidemiologists or laboratory-based medical professionals in areas relevant to HIV prevention and vaccine preparedness to HIV prevention and vaccine preparedness including HIV surveillance and prevention, blood banking, rapid HIV diagnosis, clinical (including perinatal) and vaccine trails design and implementation, laboratory support for such studies, behavioral interventions, data management and analysis. 2) To undertake intensive short term state of the art training at IHV for key Nigerian investigators and support staff to strengthen local capacity to undertake relevant collaborative research activities in HIV prevention and vaccine preparedness. It is proposed that the latter type of training activity will be the major focus of this supplement and will include in-country workshops in order to reach larger numbers of trainees and provide a forum for the application and expansion of training received by trainees. 3) Begin a process of enhancing the Center in Jos to provide training to candidates from different parts of the country and other African countries. To service these objectives a program of training activities will be developed and refined to meet the current needs of Africa's most populous country experiencing a rapid increase in non clade B HIV-1 spread and a new openness of dealing with the HIV/AIDS epidemic. A key component of this application is "south-south" collaboration via short-term training at The AIDS Support Organization (TASO) in Uganda, and at the Jos Center in the future.