课题基金 / 基金详情

CHARACTERIZATION OF INSULIN & INSULIN LIKE GROWTH FACTOR RESPONSES

CHARACTERIZATION OF INSULIN & INSULIN LIKE GROWTH FACTOR RESPONSES
胰岛素的特性
批准号：
6265406
负责人：
ALAN C MOSES
金额：
$2.98万
依托单位：
BETH ISRAEL DEACONESS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6265406
关键词：
clinical research drug screening /evaluation hormone regulation /control mechanism human subject human therapy evaluation insulin insulin sensitivity /resistance insulinlike growth factor

项目摘要

项目成果

ALAN C MOSES的其他基金

相关文献

中文摘要
翻译
1)测定不同表型重度胰岛素抵抗受试者的胰岛素抵抗程度和胰岛素分泌的完整性。2)确定有严重胰岛素抵抗的受试者对胰岛素样生长因子i亚皮下给药的反应。3)在临床或生理反应的受试者中继续rhIGF-I治疗一年，作为确定长期安全性和有效性的手段。
英文摘要
1) To determine the degree of insulin resistance and integrity of insulin secretion in subjects with various phenotypes of severe insulin resistance. 2) To determine the response of subjects with severe insulin resistance to subactue administration of insulin-like growth factor I. 3) To continue rhIGF-I therapy for an additional year in subjects who demonstrate a clinical or physiologic response as a means of determining longer term safety and efficacy.
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