CORE--BIOSTATISTICS

生物统计学核心将提供统计、数据管理和数据 为CFAR调查员提供入门支持。特别是生物统计学 核心将提供大量的 华盛顿大学生物统计系和弗雷德 哈钦森癌症研究所正在开发新的统计 艾滋病研究和CFAR生物医学研究人员的方法。此链接 这对双方都有好处。生物统计核心将提供先进的 统计方法和专业知识，这已经开发下博士。 弗莱明的艾滋病方法补助金，CFAR调查人员;临床和 利用生物统计核心的实验室研究人员将提供 数据集进行分析，这可能会促进新的 方法学补助金下的统计方法。促进和便利 这些多学科的相互作用，生物统计学核心将1） 就研究设计、表格、 设计评估和预测试，以及数据分析;提供数据输入 和数据管理服务;开发、调整和/或实施新的 统计方法;维护计算设施， 可供任何CFAR调查员使用（现场和远程登录）; 2） 在规范临床、行为和 在华盛顿大学和FHCRC艾滋病研究的统计方法; 3）增加 参与行为的个体之间的协作关系 研究和生物统计界;以及4）为以下方面提供支持 参与行为研究和生物统计学的个人 （4）为参与卫生工作的个人提供支持 通过合作联系，开展国际艾滋病/艾滋病毒研究 与卫生服务和国际核心。使用CFAR资金 作为种子，我们设想开发一个数据管理和统计 分析中心的一部分运营资金来自收费， 服务数据输入和数据管理。这将允许单个CFAR 调查人员将联合收割机在这些领域的资源， 高质量的数据库。生物统计核心还将形成一个 对于没有独立调查人员的新调查人员来说， 供资和需要高级调查员的常设调查员 生物统计专业知识，以追求创新或意外的研究 方向

The Biostatistics Core will provide statistical, data management and data entry support for CFAR investigators. In particular, the biostatistical core will provide a crucial link between the large number of biostatistical faculty at the University of Washington and the Fred Hutchinson Cancer Research Institute who are developing new statistical methods for AIDS research and the CFAR biomedical researchers. This link will benefit both groups. The Biostatistical Core will provide advanced statistical methods and expertise, which have been developed under Dr. Flemming's AIDS Methodology grant, to CFAR investigators; the clinical and laboratory researchers utilizing the Biostatistical Core will provide datasets for analysis which may motivate the development of new statistical methods under the Methodology grant. To promote and facilitate these multi-disciplinary interactions the Biostatistics Core will 1) provide statistical collaboration and consultation on study design, forms, design evaluation and pretesting, and data analysis; provide data entry and data management services; develop, adapt and/or implement new or novel statistical methods as needed; maintain computing facilities which are available (both on site and by remote login) to any CFAR investigator; 2) provide leadership in efforts to standardize clinical, behavioral and statistical methodology in AIDS research at the UW and FHCRC; 3) increase collaborative relationships between individuals involved in behavioral research and the biostatistical community; and 4) provide support for individuals involved in behavioral research and the biostatistical community; and 4) provide support for individuals involved in health services and international AIDS/HIV research through collaborative links with the health Services and International cores. Using the CFAR funding as the seed, we envision developing a data management and statistical analysis center with a portion of operating funds coming from fee-for- service data entry and data management. This will allow individual CFAR investigators to combine resources in these areas and will ensure uniform, high quality databases. The Biostatistical Core will also form a particularly valuable resource for new investigators without independent funding and for established investigators in need of advanced biostatistical expertise to pursue innovated or unanticipated research directions.