SKIN DISEASE RESEARCH

埃默里皮肤病研究核心中心（ESDRC）将培养， 协调和加强24个临床和基础 从广泛的研究学科的科学。 他们的专业知识 将集中在皮肤疾病的机制，以及皮肤 生物学，特别强调皮肤 微血管在这些过程中。 这种强调将利用 一个杰出的，多学科的内皮细胞研究小组， 生物学家，他们中的许多人以前从未将他们的专业知识集中在 皮肤 结合调查人员的专业知识和经验 在皮肤科，这组科学家集中在 ESDRC将为皮肤的作用提供新的见解， 微血管内皮细胞在各种皮肤相关的生物和 病理过程，包括急性和慢性炎症、伤口 愈合、血管生成、血管炎、卡波西肉瘤和肿瘤 转移 利用专业知识的多样性， 埃默里研究中心和服务，ESDRC将组织成 三大科学核心：1）组织培养和抗体生产 核心; 2）微量化学组分;和c）流式细胞术/细胞 分类组件;最后3）分析方法，多样性 专业知识，并为所有ESDRC调查人员和 研究人员在他们的实验室。 因此，这些 设施将大大提高生产力的参与 investigators. 此外，还进行了六项试点和可行性研究， 从提交审查的13个小组中选出。 都是 专注于真皮微血管细胞，并展示了 广泛的专业知识、技术和科学原理， 目前一般用于皮肤生物学的研究， 尤其是真皮微血管。 此外，A 综合性和多学科的浓缩方案将提供 定期的研讨会、讲习班和访问科学家报告， 这将极大地改善埃默里大学的研究和教育环境。 ESDRC的长期目标是提供新的见解， 皮肤病理和生理过程的方法， 促进和协调多学科研究方法， 各种国家认可的研究人员及其实验室。

The Emory Skin Disease Research Core Center (ESDRC) will foster, coordinate and enhance collaborative efforts among 24 clinical and basic scientistic from a wide range of research disciplines. Their expertise will be focused on mechanisms of cutaneous disease as well as cutaneous biology, with special emphasis on the role of the cutaneous microvasculature in these processes. This emphasis will take advantage of an outstanding, multidisciplinary group of endothelial cell biologists, many of whom have never before focused their expertise on the skin. Combined with the expertise and experience of the investigators in the Department of Dermatology, this group of scientists centered at the ESDRC will provide novel insights into the role of cutaneous microvascular endothelial cells in a variety of skin-related biologic and pathologic processes, including acute and chronic inflammation, wound healing, angiogenesis, vasculitis, Kaposi's sarcoma, and tumor metastasis. Capitalizing upon the diversity of expertise and existing Emory research centers and services, the ESDRC will be organized into three scientific cores: 1) the Tissue Culture and Antibody Production Core; 2) the Microchemical Component; and c) a Flow Cytometry/Cell Sorting Component; and finally 3) the analytical approaches, a diversity of expertise, and continuous training for all ESDRC investigators and the research fellows in their laboratories. As a consequence, these facilities will greatly enhance the productivity of participating investigators. Additionally, six pilot and feasibility studies have been selected from a group of 13 submitted for review. All of them are focused on dermal microvascular cells and demonstrate application of a broad spectrum of expertise, techniques,and scientific rationale not currently being utilized in the study of cutaneous biology in general, and the dermal microvasculature in particular. Additionally, a comprehensive and multidisciplinary Enrichment Program will provide regular seminars, workshops, and visiting scientist presentations that will greatly enhance the research and educational environment at Emory. The long term goals of the ESDRC are to provide novel insights and approaches into cutaneous pathologic and physiologic processes through fostering and coordinating a multidisciplinary research approach among a variety of nationally recognized investigators and their laboratories.