Dissecting the molecular mechanisms underlying muscle pathology in Duchenne Muscular Dystrophy (DMD)

杜氏肌营养不良症（DMD）是一种遗传性疾病，每年影响全球1- 3500名新生儿。这种疾病的特点是肌肉萎缩，随后在十几岁到二十多岁之间导致死亡。到目前为止，还没有治愈的方法，治疗的目的是提高生活质量。这个项目的重点是研究这种疾病背后的机制，最终获得更好的理解，以便开发更有效的治疗DMD的疗法。

Duchenne Muscular Dystrophy (DMD) is a genetic disease affecting 1-3,500 newborn males worldwide annually. The disease is characterized by muscle wasting, subsequently resulting in fatality in the late teens to the late 20's. To date there is no cure and treatments are aimed improving quality of life. This project focuses on examining the mechanisms behind the disease to ultimately gain a better understanding in order to develop more effective therapies for the treatment of DMD.